The inclusion of an ion gate in a tandem mass spectrometer allows a specific precursor ion to be selected, and the fragment ions are then used for structure analysis and to investigate chemical reactions. However, the performance of an ion gate has been judged simply by whether or not the target ion was selected. In this study, we designed, manufactured, constructed, and characterized a Bradbury-Nielsen ion gate (BNG). The actual ion selection ability, i.e. the gate function, of the BNG was measured for isotopes of Xe (z=1-6). The gate function of the BNG was 36.5±0.5 ns in width and 3-13 ns in rise and fall times. The BNG provides a simple way to select multiply charged molecular cations of small organic molecules as well as large molecules such as proteins and peptides.
Ion gate equipped in a tandem mass spectrometer is utilized to select a specific precursor ion, and its fragment ions are then assessed for both a structure analysis and an investigation of the chemical reactions. However, the performance of an ion gate has been judged simply by whether or not the target ion was selected. In this study, we designed, manufactured, constructed, and characterized a Bradbury−Nielsen ion gate (BNG). Further, the actual ion selection ability, i.e., the gate function, of the BNG was measured for the isotopes of Xe z+ (z = 1-6). The gate function of our BNG was 36.5±0.5 ns in width and 3-13 ns in rise and fall times. Our BNG provides a simple means of satisfying the requirement of selecting multiply charged molecular cations of small organic molecules as well as large molecules such as protein and peptides.
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