Background: Chest pain not yet diagnosed), has been introduced in order to describe the subset of patients without coronary ischemic etiology of their chest pain. Chest pain is one of the common reason and Acute coronary syndrome is an important cause of chest pain. Objective: To assess the Prevalence of Acute Coronary Syndrome among Patients Presenting with Chest Pain and its association with common cardiovascular risk factors. Methods: This was an observational study conducted at Faridpur Medical College Hospital, Faridpur, Bangladesh from January to June 2022 enrolling 224 participants consecutively. Participants were interviewed focusing history of hypertension, diabetes, smoking and nature of chest pain. The diagnosis of participants whether it was acute coronary syndrome or not were recorded. Prevalence of acute coronary syndrome was calculated. Linear regression analysis was done to see the correlation with tested variables. Results: Out of 224 participants, 150 (66.96%) were male. Hypertension was present in 84 (37.5%), diabetes in 60 (26.78%) and 52 (23.21%) were smoker. Mean age was 51.82±14.24 years. Seventy-five (66.96%) were male. Forty-two (37.5%) were hypertensive, 60 (26.78%) were diabetes and 52 (23.21%) were smoker. Fifty-six (50%) had nonspecific chest pain, 70 (31.25%) had atypical chest pain and 42 (18.75%) had typical chest pain. Among the participants 76 (33.93%) had acute coronary syndrome. Acute coronary syndrome showed positive correlation with age, gender, nature of chest pain, hypertension and smoking. Conclusion: Acute coronary pattern was one of the common cause of casket pain among actors visiting exigency of a tertiary cardiac centre. We set up positive correlation of age, gender, nature of casket pain, hypertension and smoking with opinion of ACS. Cases with these threat factors need strong dubitation of ACS and prompt work up when they present with casket pain so that they can get proper operation on time.
Introduction: Stroke is a leading cause of death and long-term disability worldwide. Of the total number of prevalent strokes, more than 80% are ischemic. Atherosclerosis being an inflammatory condition is associated with raised serum level of CRP. Hence the possible role of serum CRP in pathogenesis of AIS is being studied. Many studies support that serum CRP is a marker of stroke severity and prognosis. Materials and Methods: The observational and prospective study was carried out at Department of Neurology, Sheikh Sayera Khatun Medical College, Gopalganj, Bangladesh from January to December-2020.The present study ‘Serum C-reactive protein in Acute Ischemic stroke and its impact on stroke severity and prognosis. Total 51 neuroimaging confirmed cases of AIS were selected randomly for this non- interventional prospective study. Serum CRP was measured in all patients and NIHSSS was used for assessing stroke severity. Results: The mean CRP level was 21.93±3.60 mg/l and only 18% of cases were having normal CRP level. 60% of cases were having serum CRP level in the range of 3-30mg/L and 18% were having even the higher level. Age of the patient significantly correlated with the CRP level (r=0.294 at p-0.05) but the sex didn’t affect the rise in CRP (p= 0.490). Serum CRP level was affecting the stroke severity significantly (r=0.643, p-0.000).The mean CRP level in discharged patients was 10.51 ± 13.21 mg/l whereas it was 44.11 ± 29.7 mg/l in those who died in the hospital. Thus CRP level affected mortality of acute ischemic stroke significantly. (p-0.00). Conclusion: CRP is raised in most of the patients of acute ischemic stroke and its elevation reveals the underlying inflammation causing atherosclerosis as well as CRP as a marker of brain injury. Serum C-reactive protein elevation is associated with more severe stroke and poor prognosis.
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