Oxygenated lycopenes, (2S*,5S*,6R*)-2,6-cyclolycopene-1-methoxy-5-ol, (2S*,5S*,6R*)-1,16-didehydro-2,6-cyclolycopene-5-ol and (3R,6'R)-3-hydroxy-3',4'-didehydro-beta,gamma-carotene (anhydrolutein I) were isolated from tomato puree. The structures of these compounds were elucidated on the basis of spectroscopic evidence.
We investigated in vitro the reactivity of lycopene toward peroxynitrite and identified the reaction products after scavenging peroxynitrite. On the basis of these studies, we propose a mechanism for peroxynitrite scavenging action of lycopene.
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