The purpose of this investigation was to determine the effects of Nd:YAG laser treatment on the permeability of dentine. Forty dentine discs were prepared by horizontal sectioning through the middle coronal third of freshly extracted non-carious third molars. After the removal of the pulp the discs were finished w^ith 600 grit and divided into three test groups and one control group (« = 10). For the test groups three different laser power settings were chosen: test group A: 3 X 60 sec, 60 mJ; test group B: 3 X 60 sec, 90 mJ; test group C: 3 X 60 sec, 120 mJ. No laser treatment was performed on the control group. In a two-chamber system the filtration rate of dentine tubules from an exactly defined area of the specimens was measured using a radioactive Ringer solution under a pressure of 30 cm H2O.Permeability measurements were carried out three times prior to lasing, three times immediately following laser treatment and six times after the application of phosphoric acid. Analysis of variance showed a significant influence of the Nd:YAG laser treatment on the permeability of dentine (P < 0 001). The mean quotient of non-treated control vs. lased dentine was 2-19 ± 0-86 for the 60 mJ beam, 1-49 ± 0-88 for the 90 mJ beam, and 2 04 ± 217 for the 120 mJ beam. Etching the lased surfaces had a statistically significant influence on the permeability of the dentine only in the 60 mJ group (P < 0 001). The data show that the Nd:YAG laser treatment often increases the permeability of smear layer covered dentine but moderates the increase of permeability after etching the surface with phosphoric acid.
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