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Materials in rotating machinery are typically subjected to vibratory loading from a number of sources which, in turn, is superimposed on mean stresses which result primarily from steady-state centrifugal loads. In addition, components subjected to vibratory stresses can sustain damage during manufacturing, break-in cycles, or during service such as from foreign objects, fretting, or other types of wear. The combination of vibratory and 'steady' stress levels can, for certain load levels, produce low cycle fatigue damage in addition to the damage produced from the high frequency (HCF) vibratory loading since the 'steady' stresses are actually low cycle fatigue (LCF) which results in one cycle for every startup and shutdown operation. Design for HCF is generally based on a Goodman diagram which takes into account the vibratory as well as the steady stress amplitudes for fatigue runout or fatigue under a given number of cycles. It does not, however, take into account the combined effects of LCF and HCE In this investigation, the combined effects are demonstrated analytically by numerical examples which consider both the initiation and propagation phases of fatigue. In addition to the analysis of LCF/HCF interactions, considerations which must be accounted for in design are reviewed in light of a number of failures of components in service in U.S. Air Force fighter engines. A critical assessment of the concepts embedded in the use of the Goodman diagram is presented. Comments on the limitations on the use of a Goodman diagram for design are provided. Some suggestions are offered for the improvement of the design methodology for HCF which involve both damage tolerance considerations and methods for assessing and improving the margin of safety.