A total of 65 patients with clinically significant diagnoses of remitting multiple sclerosis in the stage of remission were studied. Neurological status was investigated with assessment on the FS and EDSS scales, with neuropsychological testing, and MRI scans (1.5 T). The severity of brain atrophy (in terms of the parenchyma volume) and the total volume of foci on T2 images were assessed as proportions of intracerebral volume. The severity of neurological deficit depended on the volume of intratentorial focal lesions and the level of brain atrophy. Cognitive disorders were identified in 89% of patients, and the severity of these was associated with the level of atrophy and the volume of foci on T2 images in the dominant hemisphere.
The present work examines the change in color reflection in psychogenic pain in patients with somatoform disorders (SFD) during psychotherapeutic treatment, for which empatho-techniques were used. At the start and end of the course the psychophysiological condition was determined according to psychological parameters and assessment of bioelectrical brain activity. All initial indicators for the patients significantly differed from those for the healthy subjects. At the same time, color reflection in the psychogenic pain was characterised by colors in the longwave part of the spectrum, in contradistinction to healthy subjects for whom achromatic and shortwave colors predominated. After the completed course patients with SFD had a significant improvement of all psychophysiological indicators and a lack of color reflectons in the longwave part of the spectrum. The data obtained permits the proposition that there exists a link between the psychogenic pain, its color reflection and anxiety, and also changes in the functional condition of the CNS.
A total of 34 patients with multiple sclerosis (MS) aged 14-52 years, with disease onset at age 24.3 +/- 7.5 years, were studied. Disease severity on the Kurtzke scale (EDSS) was 3.6 +/- 1.7 points. Seven patients were in exacerbation of MS and 27 were in remission. Personality characteristics in terms of MS-associated maladaptation were studied using a modified MMPI (the SMPT method). Neurotic, psychotic, and mixed types of maladaptation were identified. Measures of brain metabolic activity were simultaneously determined (in terms of the rate of glucose utilization) by positron emission tomography (PET). Data were obtained on the relationship between the activity of metabolic processes in the frontal, temporal-parietal, and limbic areas of the cerebral cortex and different variants of personality maladaptation and, respectively, with different personality profiles in the SMPT.
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