Background: Pregnancy induced hypertension is an important cause of maternal and fetal morbidity and mortality affecting 5-10% of pregnancies.PIH is more frequently associated with elevated TSH. Hypothyroidism is one of the causes of hypertension in nonpregnant state. Hypertension is completely reversible in 50% cases of hypothyroidism by levothyroxine therapy. Treating hypothyroidism in pregnancy may help to reduce PIH prevalence. Objectives-This is an observational study to find out association of PIH with hypothyroidism and to know result of levothyroxine treatment on PIH prevalence and its severity. Methods: 75 singleton pregnancies with PIH admitted to labour ward, evaluated with their TSH status in groupA. In Group B, 75 singleton pregnancies with subclinical or overt hypothyroidism treated with levothyroxine to maintain euthyroid state throughout pregnancy and observed for development of PIH. Overt hypothyroidism considered when TSH value ≥10 and subclinical hypothyroidism when TSH value between 3 and 10.. Result: Overt and subclinical hypothyroidism was present in 12% (9 out of 75) and 57.3%(43 out of 75) cases of PIH respectively. In group B, all hypothyroid pregnancies treated with levothyroxine throughout pregnancy, prevalence of PIH was 6.66% (5 out of 75) . Significant association of PIH and hypothyroidism demonstrated by Fisher's exact test (p<0.001). PIH prevalence significantly reduced in treatment group demonstrated by chi square test (p<0.001). Conclusion: Subclinical and overt hypothyroidism prevalence is significantly high among PIH patients. Treating subclinical and overt hypothyroidism in pregnancy, reduces prevalence of PIH and its severity.
Background: Intrauterine fetal death is a very tragic event for the parents and a great challenge to the obstetrician. It contributes to perinatal mortality and detail analysis of it may help to reduce the still birth rate in India. The aims and objectives of the study is to find out the prevalence, socio-demography, maternal risk factor and fetal characteristics of intrauterine fetal demise cases. Methods: This is a retrospective observational study carried out in Institute of Medical Science and SUM Hospital Bhubaneswar from October 2014 to April 2015. Ante partum events leading to fetal demise were recorded, socio-demographic and clinical characters were noted and analysed. Results: There were 2899 deliveries and 90 fetal deaths in this period. The incidence of IUFD was 31.04/1000 live births in our study. Conclusion: Pregnancy induced hypertension, severe anaemia; abruption of placenta, congenital malformation of the fetus is the main cause of fetal demise. All the main causes of fetal death observed here is preventable. Proper preconceptional counselling, antenatal care is mandatory to reduce the still birth rate by 2030.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.