Data on the linkage relations of the ‘ridges off-the-end’ syndrome and the Nelson syndrome with many marker loci are presented. Other families with these syn dromes will need to be tested before any definite conclusions can be reached.
A study of the distribution of the summed (right plus left) a-b ridge count in 1,000 normal subjects showed a significant deficit of counts at the two ends of the range. In males the distribution was significantly different from a normal distribution, but in females a similar trend did not reach statistical significance. No significant sex difference was found, although it is known that abnormal sex chromosome complements may affect the a-b ridge count. The influence of the sex chromosome complement on the a-b ridge count appears to be smaller than the effect of the sex chromosome complement on the total finger ridge count. The a-b ridge count is probably also less genetically determined than the total finger ridge count.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.