This is the first study that seems to indicate that cytogenetic findings have prognostic significance in AILD-type T-cell lymphoma. These results must be proven in prospective studies of homogeneously treated patients.

Background: Blood group A substance was detected on red cells of a patient who received a bone marrow transplant from a blood group 0 donor 3.5 years ago. Material and Methods: Peripheral blood was investigated by conventional serological techniques, fluorescence in situ hybridisation, and polymerase chain reaction. Results: All peripheral blood cells are of donor origin. Anti-A and not anti-AB of blood group 0 individuals can be absorbed to the group 0 red cells of the patient. Conclusion: We suppose that the patient’s residual serum A transferase attaches the appropriate sugar to substance H on the red cell membrane to form substance A.

AML with eosinophilia belongs to the morphologic cytogenetic entity M1/M2 t(8;21) with the involvement of the genes AML1/ETO. These eosinophils differ only slightly from normal eosinophils with one rare exception i.e. Auer rods in eosinophils which has only been found on peroxidase staining: This subtype belongs to the good prognosis group of AML. AML with inv(16) (mostly M4Eo) per se is a morphologic-cytogenetic entity with inv(16),--rarely t(16;16), and the genes MYL 11/CBF beta involved. The eosinophils show special abnormalities. AML with inv(16) also belongs to the good prognosis group of AML.

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