30 A. Bock et al.: MR-Perfusionsmessung bei intrakraniellen MeningeomenKlin Neuroradiol 1998;8:30--4,1 (Nr I) Quantification of the Embolization Effect in Intracranial Meningeomas by T2*-Weighted MR-Perfusion MeasurementSummary. It is the aim of this investigation to test if the MR-perfusion measurement is suitable for the quantification of the embolization effect in intracranial meningeomas and if areas with residual perfusion after percutaneous transarterial embolization (PTE) can be identified. Preoperative stepwise PTE with PVA particle suspension was performed in 23 patients (15 female, 8 male, ages: 34 to 82 years) with 24 intracranial supratentorial meningeomas (basal: 9, convexity: 8, falx: 7; 3.5 to 9.0 cm in maximum diameter). The perfusion studies were performed with a contrast enhanced fast T2*-weighted FFE-sequence before and 24 to 48 h after PTE. A calculation algorithm for the adjustment of interstitial contrast media distributions was developed in order to calculate the perfusion data. Dependent on the size of the meningeoma up to 3 ROI (matrix, centre and periphery close to cortex) were referenced against the contralateral cortex. The detected reduction of perfusion after PTE was matched with angiographical data (reduction of perfusion, additional pial-cortical feeding). The perfusion of meningeomas with angiographical detectable pial-cortical supply (pcF, 11/24) is well-balanced over all regions. In meningeomas without pcF (13/24) centre and pe¡ show a significant lower perfusion if compared to the matrix (p < 0,05). The reduction of perfusion after PTE by MR-perfusion measurement in the matrix and centre is comparable (65 vs. 76%), regardless of the entire estimation in angiography. However, residual perfusion in periphery is significantly higher (p < 0,05). This is caused either by a low entire perfusion of meningeoma and/or by additional pial-cortical supply. The MR-perfusion measurement controls the result of PTE at intracranial meningeomas with effectiveness. Significantly perfused regions following PTE can be identified. Insights into the supplying role of different feeding areas ate gained. In meningeomas with low perfusion and/or additional pial-cortical supply the PTE effect on the periphery close to the cortex is frequently missed.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.