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Cervical teratomas have been defined and one new case is now added to the 116 cases previously reported. We have been able to find only six reports of malignant teratoma in the literature so far. The problem of diagnosis and obstetric management are discussed briefly. The incidence of appearance of the tumor is described and the likelihood of hydramnios or of acute obstructive symptoms of the trachea and esophagus at birth are discussed. The differential diagnosis includes cystic hygroma, congenital goitre, bronchial cyst, lymphangioma, neuroblastoma, parotid tumor and carcinoma of the thyroid. The object of this review is to present a synoptic description of these tumors, their clinical manifestations, management, treatment and prognosis, so that it may afford the attending obstetrician a guideline in understanding this rare entity.

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Rectal Biopsy-Brett and Berry MEDICAL JOURNAL 403 and that increasing refinement of chemical and other investigations may in time render biopsy obsolete also in many cases of neurolipidosis. Pneumoencephalography was of no value in selecting cases for rectal biopsy, since it showed cerebral atrophy with equal frequency in patients whose biopsies later did and did not show diagnostic changes. No diagnostic abnormalities were found on rectal biopsy in patients without dementia, a positive family history of relevant disease or other features pointing strongly towards a specific neurological condition.We thank the physicians and surgeons of the Hospital for Sick Children, Great Ormond Street, for permission to publish details of patients in their care.

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