We demonstrate a miniature, near-infrared microscope (λ = 785 nm) that uses a novel dual axes confocal architecture. Scalability is achieved with post-objective scanning, and a MEMS mirror provides real time (>4 Hz) in vivo imaging. This instrument can achieve sub-cellular resolution with deep tissue penetration and large field of view. An endoscope-compatible version can image digestive tract epithelium to guide tissue biopsy and monitor therapy.
We report a low-threshold, narrow-line THz-wave parametric oscillator with an intra-cavity grazing-incidence grating and a 1-mm thick, 45-mm long lithium-niobate planar waveguide. When pumped by an actively Q-switched Nd:YAG laser, the threshold energy and intensity of the parametric oscillator were about 2.2 mJ and 70 MW/cm(2), respectively. The linewidths of the output THz wave were 12 and 134 GHz with and without the intra-cavity grating, respectively.
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