Objectives: To describe the outcome and risk factors for Urinary Tract Infection (UTI) caused by Extended Spectrum Beta Lactamase (ESBL) producing microorganisms, in children aged 2 months to 15 years, at a tertiary care centre in South India over a period of 1 year.Method: During the study period, there were 352 children with UTI, of which 100 had ESBL UTI and they were included in the study. These 100 children were analysed for risk factors of UTI, nature of treatment, duration of hospital stay and response to treatment and these were recorded in the preformed proforma. Urine routine, urine culture and sensitivity, ultrasonogram, micturating cystourethrogram and dimercapto-succinic acid (DMSA) scan were done for all patients. If colony count was ≥10 5 colony forming units (CFUs) /ml on clean catch sample or urobag sample or any number in catheterized or suprapubic sample with significant ESBL strain growth on urine culture were recorded along with sensitivity pattern. Follow up was done for 3 months.Results: Age and sex distribution of ESBL UTI were 20 (37%) boys and 13 (28.2) girls in the age group 2 months to 2 years, 15 (27.7%) boys and 15 (32.6%) girls in the age group 2 to 5 years, 12 (22.2%) boys and 5 (10.8%) girls in the age group 5 to 10 years and 7 (11.9%) boys and 13 (28.2%) girls in the age group 10 to 15 years. Common risk factors for ESBL UTI in our study were recent antibiotic use within the last 3 months (55%), _________________________________________
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