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We studied the effect of systemic transplantation of human stem cells from various tissues on cognitive functions of the brain in rats during the delayed period after experimental brain injury. Stem cells were shown to increase the efficacy of medical treatment with metabolic and symptomatic drugs for recovery of cognitive functions. They accelerated the formation of the conditioned defense response. Fetal neural stem cells had a stronger effect on some parameters of cognitive function 2 months after brain injury. The efficacy of bone marrow mesenchymal stem cells from adult humans or fetuses was higher 3 months after brain injury.

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The dependence of free layer coercivity on the angle between easy axis and applied magnetic field was studied on [Ta, (Ni80Fe20)60Cr40]/ Ni80Fe20/Co90Fe10/Cu/Co90Fe10/Mn75Ir25/Ta spin valves with various interlayer coupling. Sharp decrease on the angle was observed for ferromagnetically coupled spin valves. The coercivity was reduced down to tenth of Oersted without any decrease of GMR-effect by forming nearly parallel anisotropy configuration. The angles at which the transition from hysteretic to anhysteretic magnetic reversal takes place are detected by analyses of the angle dependence of coercivity. Interpretation of experimental data is based on Stoner-Wohlfarth coherent rotation approach.

We studied the effect of transplantation of human stem cells from various tissues on reparative processes in the brain of rats with closed craniocerebral injury. Combined treatment with standard drugs and systemic administration of xenogeneic stem cells had a neuroprotective effect. The morphology of neurons rapidly returned to normal after administration of fetal neural stem cells. Fetal mesenchymal stem cells produced a prolonged effect on proliferative activity of progenitor cells in the subventricular zone of neurogenesis. Adult mesenchymal stem cells had a strong effect on recovery of the vascular bed in ischemic regions.

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