Sorghum malts, which are important ingredients in traditional fermented beverages, are commonly infected by mycotoxigenic fungi and mycotoxins may transfer into the beverages, risking consumers’ health. Liquid chromatography–tandem mass spectrometry was used to determine variation of fungal metabolites in 81 sorghum malts processed for brewing of Namibian beverages, otombo (n = 45) and omalodu (n = 36). Co-occurrence of European Union (EU)-regulated mycotoxins, such as patulin, aflatoxins (B1, B2, and G2), and fumonisins (B1, B2, and B3) was detected in both malts with a prevalence range of 2–84%. Aflatoxin B1 was quantified in omalodu (44%) and otombo malts (14%), with 20% of omalodu malts and 40% of otombo malts having levels above the EU allowable limit. Fumonisin B1 was quantified in both omalodu (84%) and otombo (42%) malts. Emerging mycotoxins, aflatoxin precursors, and ergot alkaloids were quantified in both malts. Notably, 102 metabolites were quantified in both malts, with 96% in omalodu malts and 93% in otombo malts. An average of 48 metabolites were quantified in otombo malts while an average of 67 metabolites were quantified in omalodu malts. The study accentuates the need to monitor mycotoxins in sorghum malts intended for brewing and to determine their fate in the beverages.
The scourge of microbial infectionsMicrobial infections are a major cause of morbidity and sometimes mortality, especially in developing countries such as Namibia. Severe poverty is the root cause of this undesirable situation as it leads to malnutrition, inadequate sanitation and consumption of unclean food and drink. This, compounded by lack of education and access to primary healthcare, results in infections by microorganisms such as viruses, bacteria, fungi and protozoa (Table 4.1).The most vulnerable to infectious diseases caused by microbial agents are children under the age of five, where 66% of deaths in this age group are a result of such diseases; 34% of all deaths are attributed to infectious diseases. This was underscored by WHO's (World Health Organization's) Regional Director for Africa, Luis Gomes Sambo, in 2011 when he said 63% of deaths on the continent were caused by microbial infections, with HIV/AIDS accounting for 38.5% of these (Anon, 2012). Thus, the most vulnerable groups are young children and individuals whose immune systems are compromised by HIV infection (Table 4.2).Community-acquired bacteraemia is a major cause of death in children at rural sub-Saharan district hospitals. A study by Berkley et al. (2005) showed that 12.8% of infants younger than 60 days had bacteraemia. Escherichia coli and group b streptococcus were the predominant infectious agents. In those older than 60 days, 5.9% were infected with Streptococcus pneumoniae, Salmonella species, Haemophilus influenzae or E. coli. In Gambia, children under five years have a 2.5% risk of
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