were included in the study. Patients in group-A received antibiotic prophylaxis whereas patients in group-B did not receive any antibiotic prophylaxis. Results: Mean age of the patients was 44.91±13.37 and 42.28±13.76 years in group-A and B, respectively. In group-A there were 152 patients (46.7%) and in group-B 148 patients (45.5%) were males. In group-A 173 patients (53.3%) and in group-B 177 patients (54.5%) were females. In group-A, superficial site infection was seen in 4 patients (1.2%) and in group-B superficial site infection was observed in 13 patients (4.0%). The difference between two groups was statistically significant (p=0.027). Mean duration of symptoms was 5.75±0.50 and 5.77±0.92 days in group-A and B, respectively. Stratification with regard to age, gender and duration of symptoms was carried out. Conclusion:In conclusion, we recommend the use of pre-operative prophylactic antibiotics for patients who are undergoing elective low-risk laparoscopic cholecystectomy inorder to prevent postoperative infectious complications. Key words:Laparoscopic Cholecystectomy, Antibiotic Prophylaxis, Surgical Site Infection. Article Citation: Nauman SM, Haroon Y, Ahmad A, Saleem I. Surgical site infection; prophylactic antibiotics in laparoscopic cholecystectomy to reduce surgical site infection.
Objectives: To compare antibiotic prophylaxis in preventing frequency ofpostoperative surgical site wound infection rate in low risk laparoscopic cholecystectomywith controls. Study design: Randomized Controlled Trial. Setting: Department of Surgery,Combined Military Hospital, Rawalpindi. Duration of study: This study was conducted from11-07-2015 to 10-01-2016. Subjects and methods: A total of 650 patients (325 in each group)were included in the study. Patients in group-A received antibiotic prophylaxis whereas patientsin group-B did not receive any antibiotic prophylaxis. Results: Mean age of the patients was44.91±13.37 and 42.28±13.76 years in group-A and B, respectively. In group-A there were152 patients (46.7%) and in group-B 148 patients (45.5%) were males. In group-A 173 patients(53.3%) and in group-B 177 patients (54.5%) were females. In group-A, superficial site infectionwas seen in 4 patients (1.2%) and in group-B superficial site infection was observed in 13patients (4.0%). The difference between two groups was statistically significant (p=0.027).Mean duration of symptoms was 5.75±0.50 and 5.77±0.92 days in group-A and B, respectively.Stratification with regard to age, gender and duration of symptoms was carried out. Conclusion:In conclusion, we recommend the use of pre-operative prophylactic antibiotics for patientswho are undergoing elective low-risk laparoscopic cholecystectomy inorder to prevent postoperativeinfectious complications.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.