Utilizing full potential of IBX, a mild, selective, and facile method has been developed for the direct conversion of olefins into the corresponding a-bromo ketones by using 1.1 equivalents each of o-iodoxybenzoic acid and tetraethylammonium bromide.
Biologically important process of oxidation of amidoximes has been investigated using IBX (oiodoxybenzoic acid) and combination of IBX with TEAB (tetraethylammonium bromide). The reaction proceeds with high % conversion leading to selective formation of amide and nitrile depending upon the combination of reagents.
Alcohols Using Hypervalent Iodine(V)-Mediated Oxidations. -Hypervalent iodine(V) reagents in combination with TosOH or MesOH are used for the direct preparation of α-tosyloxy and α-mesyloxy ketones, resp., from secondary alcohols. The reactions are also possible under solvent-free conditions. -(DESHMUKH, S. S.; HUDDAR, S. N.; AKAMANCHI*, K. G.; Synth. Commun. 39 (2009)
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