Acute poisoning by potassium permanganate is a rare condition with high morbidity and mortality. Diagnosis of the condition relies on a history of exposure or ingestion and a high degree of clinical suspicion. Oxygen desaturation and the presence of methemoglobin are also helpful indicators. Since no specific antidote is available, treatment is mainly supportive. Few cases have been reported in the literature following potassium permanganate ingestion, whether intentional or accidental, and most of the patients in these cases had unfavorable outcomes, which was not the case in our patient. Our patient, a 73-year-old male, purchased potassium permanganate over the counter mistaking it for magnesium salt, which he frequently used as a laxative. Several hours after he ingested it, he was admitted to the endocrine department at King Hussein Medical Center, Jordan, with acute rapidly evolving shortness of breath. During hospitalization, his liver function tests deteriorated. Since he was diagnosed early and managed promptly he had a favorable outcome.
In December 2019, the WHO China Country office was informed of an outbreak of pneumonia of unknown etiology, in Wuhan city. The pathogen was later identified as a member of the β-coronaviridae family, and the disease it caused was named Covid-19. The outbreak rapidly evolved over the next few months to become a pandemic that resulted in drastic effects on global healthcare and economy. Diabetic patients were affected equally as non-diabetic individuals; however, the impact of the disease was much worse amongst them. We aim to briefly review the incidence and characteristics of Covid-19 infection among diabetic patients, elaborating into the pathophysiology of the disease and the possible mechanisms which may explain the severity of the disease amongst them, through a review of published articles in Pubmed, Google Scholar and Cochrane databases, till the first of January 2022.
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