BACKGROUNDMultiple myeloma is a bone marrow based plasma cell neoplasm that often presents with multifocal and disseminated involvement. Not surprisingly bone marrow examination is a key to its diagnosis along with laboratory and clinical data. Morphology of plasma cells assumes significance along with plasma cell quantity in distinguishing multiple myeloma from reactive plasmacytosis. At times the heterogeneity in plasma cell morphology leads to misdiagnosis as other neoplasms like lymphomas.The present study is an attempt to evaluate the various morphological patterns seen in bone marrow of cases diagnosed as multiple myeloma.
BACKGROUNDPosterior cranial fossa houses the cerebellum and brainstem that contains all cranial nerve nuclei and many afferent fibre tracts that connect the brain with the rest of the body. Early diagnosis of posterior fossa lesions is vital to prevent complications like herniation and brainstem compression that is invariably fatal.The present study is an attempt to collect the demographic profile and types of posterior fossa lesions. We also assessed the extent of correlation between clinical and radiological diagnosis and the diagnosis on histopathology.
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