Ectopic pregnancy is defined as pregnancy outside uterine cavity. Of all ectopic pregnancy, tubal ectopic is most common. Most cases today are diagnosed early and hence timely treatment is possible. In stable patients, medical line of management with methotrexate can be used. With early diagnosis and medical line of treatment, use of injectable methotrexate is on rise. Being aware of characteristics of methotrexate like mechanism, dosage, side effects and contraindications, appropriate patient selection and watchful monitoring will help reduce methotrexate induced toxicity.
Protein molecules which bind and inhibit the activity of serine protease enzymes are known as serine protease inhibitors. These are proteolytic enzymes which possess triad of aspartic acid, histidine and serine in their active site. They take part in a variety of physiological processes like protein digestion in intestine, blood clotting, muscle
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