The spot blotch disease caused by Bipolaris sorokiniana (Sacc.) Shoem is one of the most important foliage disease of wheat crop. This disease appears in almost all wheat growing areas of the world. In Northern part of west Bengal this disease causes severe yield loss every year. For the management of spot blotch disease of wheat five chemical fungicides was used. Plant disease intensity decreased with the application of different treatment over untreated control.The lowest AUDPC was recorded in T4 (Propiconazole@ 1ml/l)260.8 followed by T5 (Tebuconazole@1ml/l) 293.21 and T3 (Carbendazim+Mancozeb @) 2.5g/l) 376.54. Maximum AUDPC was recorded (563.27) under T1 (Untreated/control). Due to the application of Propiconazole, spot blotch disease reduce up to 60.18% and increase chlorophyll contain of the plant, increase different morphological traits of wheat crop as well as also ultimately increase yield up to 35.02%.
The discovery of antibiotic to combat bacterial infections, has been a lifesaving discovery. But, gradually due to more dependency and continuous use of antibiotics, instead of becoming a boon, it gradually tends more towards the negative aspect of development of antibiotic resistance. Eventually, the bacteria started developing resistance to the antibiotics. This has opened the door for researchers to learn more about how antibiotic resistance genes (ARG) evolve and lead to antibiotic resistance in bacteria. The present review focused on the use of two major antibiotics which are widely used now a days (Streptomycin and Oxytetracycline) emphasizing more on the mechanism of development of resistance in the bacteria and their impact on antibiotic resistance. Researchers are also trying continuously to develop some alternative antimicrobial drugs which will have minimum risk of antibiotic resistance. Antibiotic resistance is a risk that must be considered; else, a bleak future awaits
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