Background:
Mechanical plaque removal is considered the gold standard for controlling and prevention of plaque and gingivitis. The present study was conducted to evaluate the efficacy of commercially available herbal dentifrices in comparison with conventional dentifrices against two of the common oral microbes, namely
Streptococcus mutans
and
Candida albicans
.
Materials and Methods:
To determine the antimicrobial properties of individual dentifrices, the zone of inhibition on the blood agar plates was measured and also disc diffusion method was used for testing the antibacterial properties for which a thin paper disc containing the antimicrobial agent was applied on a culture of bacteria grown on agar media. Each dentifrice was tested in 50% concentration (1:1 dilution [50% w/w] using sterile deionized distilled water/half strength) and 100% concentration (full strength). The blood agar plates were then incubated aerobically at 37°C. The measurement of zone of inhibition was done after 24–48 and 72 h on the underside of the Petri dishes using Vernier calipers.
Results:
At 50% concentration, Regimen B2 showed the maximum zone of inhibition which was closely followed by Regimen A1 for
S. mutans
, whereas at 100% concentration, Regimen A1 showed better effects. For
C. albicans
, it was observed that Dabur red toothpaste showed the significantly higher zone of inhibition at 50% concentration when the concentration was made 100% and also Dabur red toothpaste showed the maximum zone of inhibition.
Conclusion:
This concluded that the herbal dentifrices are equally and sometimes better than the conventional ones.
Rationale:
Gorlin-Goltz syndrome (GGS) has a wide range of expressivity, with a majority of cases being first diagnosed from the oral findings. Early intervention can reduce its severity.
Patient Concerns:
The primary complaints of all the patients were pain and swelling. Clinical examination with radiological and histopathological evaluation confirmed the diagnosis.
Diagnosis:
This series presents the six cases of GGS treated over a time frame of five years (2018–2022).
Treatment:
The treatments range from enucleation, chemical cauterisation and peripheral ostectomy to aggressive modalities such as resection and reconstruction.
Outcomes:
This series comprises of six patients with ages ranging from 12 to 42 years, four of which were female and two were male presenting minimal expression to highly aggressive forms and its unpredictable frequent manifestation.
Take-Away Lessons:
This emphasises the significance of long-term periodic follow-up and genetic screening for early detection, thereby reducing the intensity and aggressiveness of the disease.
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