Background Antioxidant supplementation may provide protection against negative health consequences of oxygen-free radicals caused by aerobic and re-sustained exercise. The aim is to find out the efficacy of antioxidant rich nutrient bar supplementation on the antioxidant status and physical fitness components of athletes. Method Forty track and field athletes were selected using convenience sampling technique. The Human Research Ethics Committee of PSG College of Arts and Science, Coimbatore approved the study. Voluntary participation of the subjects was emphasized and a written consent was obtained from them in order to be included in the study. An interview schedule was formulated to collect general information such as name, age, gender, and academic qualifications, as well as information pertaining to the types of sporting activity, duration of the activity per day, number of years involved in the respective sports and level of participation (district/state/national). Nutrient bars each weighing 50gm were prepared with rolled oats, pumpkin seeds, dehydrated carrots, flax seeds, peanuts, almonds, honey and date syrup as ingredients. Each athlete was provided with two bars containing 110 mg of antioxidant. The prepared bars were analyzed for their total anti-oxidant content using DPPH method. The experimental group (n = 20) was supplemented with the formulated nutrient bars every day for a period of 3 months, and the control group (n = 20) with a placebo. Bio-chemical parameters namely GSH, GSH-px, SOD, vitamin C, serum LPO and physical fitness tests such as 12 minutes test, speed test, step test, push-ups test, vertical jump test and hexagon agility test were assessed at baseline and after 90 days. Statistical analysis was performed using SPSS (version 15). ResultsThe mean age was 18 ± 3.2 yrs. Sixty percent of the selected athletes were males and 40 % females. The main source of nutrition information was from coaches (56 %) and magazines (30 %). The athletes of the experimental group, when compared with the control group, showed a significant increase in serum levels from 37.42 ± 12.01 units/min/ml to 42.08 ± 13.16 units/min/ml of SOD (p = 0.000). LPO increased from 2.89 ± 0.82 μg/ml to 3.80 ± 1.37 μg/ml (p = 0.005), GSH increased from 209.76 ± 8.17 μg/ml to 244.58 ± 33.36 μg/ml (p = 0.000). The mean levels of vitamin C and GSH-px decreased minimally in the experimental group but significantly in the control group. Significant improvement in all six physical fitness tests namely 12 minutes test (from 1.44 ± 0.142 to 1.56 ± 0.134) , speed test (from 6.5940 ± 0.258 to 6.7435 ± 0.25) step test (from 68.65 ± 5.51 to 78.35 ± 4.004) push-ups (from 22.25 ± 3.97 to 29.70 ± 3.40), vertical jumps test (from 60.00 ± 5.620 to 63.75 ± 6.043) and hexagon agility tests (from 12.255 ± 0.42 to 12.400 ± 0.51) were observed in the experimental group). However in the control group, the improvements were significant only in the 12 minutes test, step test and speed test. Conclusion Supplementation of athletes with antioxidant-rich...
Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder with various health complications like menstrual irregularities, hirsutism, acne, obesity, and insulin resistance. It is becoming a prominent cause of infertility among women worldwide. A woman's diet may ultimately affect her fertility, particularly ovulation. The assisted reproductive technologies for the treatment of infertility may cost high and have an adverse effect. To reduce the adverse effects, the novel dietary supplements are the new alternative approach to treat PCOS. Novel dietary supplements enriched with phytoestrogen help in alleviating the symptoms of PCOS such as improvement in ovulation, reduced blood glucose level, reduced stress level, and decreased weight. The present study was aimed to develop novel dietary supplements for women with PCOS. Aim and objective: To develop novel dietary supplements for women with PCOS by using underutilized ingredients. Materials and methods: Three different types of novel dietary supplements (supplement 1, supplement 2, and supplement 3) were developed under proper hygienic conditions. The organoleptic properties of the developed supplements were evaluated by the group of panel members. Followed by organoleptic evaluation, nutrient compositions were analyzed for the finalized supplement (supplement 3). Results: The nutrient composition of the finalized supplement was analyzed by using the standard procedure of AOAC ( 2016) and it is reported that the supplement is enriched with omega-3-fatty acid, polyphenols, flavonoids, selenium, iron, vitamin-A, and fiber. One-way ANOVA was used to analyze the significance between the formulated supplements and reported that the formulated supplements were statistically significant (p < 0.05). Conclusion:The study signifies that novel dietary supplements rich in phytoestrogens like polyphenols and flavonoids can be used for the treatment of PCOS. Clinical significance: Intake of developed supplement could result in regulation of menstruation and improvement in ovulation.
Polycystic ovary syndrome (PCOS) is a diverse condition that has distinct signs and symptoms such as hyperandrogenism and chronic anovulation. It is a major hormonal disorder that affects the health-related quality of life and mental health of young women. The etiology of PCOS still remains uncertain but insulin resistance is one of the major factors seen in PCOS individuals which are characterized by the presence of acanthosis nigricans. Dietary interventions and lifestyle modification are being considered to be a first-line treatment for women with PCOS. Proper diet, adequate nutritional status, and following a physical activity routine help in alleviating the symptoms of PCOS. Dietary interventions should focus on weight management and insulin regulation. An abnormal gut microbiome function results in ovarian dysfunction, immune changes, insulin resistance, and disruption in bile synthesis. Therefore, gut health of women suffering from PCOS should be prioritized and interventions that improve the gut health should be followed. This systematic review is performed to investigate the association between micronutrient supplementation and PCOS. The related articles were searched using the databases PubMed, Science Direct, and Google Scholar. All the studies involving micronutrient supplementation and PCOS were included in this systematic review. Micronutrient supplementation was significantly inversely associated with improving PCOS prognosis. The main finding of the systematic review is that it concludes there is a direct association between micronutrient supplementation as it helps in alleviating the symptoms and maintaining a proper lifestyle in women with PCOS.
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