CytoSorb® (CytoSorbents Corporation, USA) is a novel sorbent hemoadsorption device for cytokine removal. The aim of this study was to examine the clinical use of CytoSorb® in the management of patient with septic shock. We used this device as an adjuvant to stabilize a young patient with multi-organ failure and severe sepsis with septic shock. A 36-year-old female patient was hospitalized with the complaints of malaise, general body ache, and breathing difficulty and had a medical history of diabetes mellitus type II, hypertension, obstructive sleep apnea, hypothyroidism and morbid obesity. She was diagnosed to have septic shock with multi-organ dysfunction (MODS) and a low perfusion state. CytoSorb® hemoadsorption column was used as an attempt at blood purification. Acute physiology and chronic health evaluation score, MODS score, and sequential organ failure assessment score were measured before and after the device application. CytoSorb application as an adjuvant therapy could be considered in septic shock.
Background: The relationship between uric acid and microalbuminuriain healthy adults without other cardiovascular risk factors may help to clarify the role of uric acid in cardiovascular disease. In this study, we examined that elevated serum uric acid level was associated with microalbuminuria.Subjects and Methods: Study was done on both male and female prehypertensive patients of age more than 18 years and less than 60, admitted in wards and attending OPD. Controls were normotensive patients admitted in wards who were matched for age, sex and confounding factors.Results: Hyperuricemia was found in 53(15.14%) patients with prehypertension compared to 32 (9.14%) patients with normal BP. Thus hyperuricemia was seen in patients of prehypertension which was highly significant as P<0.001.Conclusion:In conclusion we found that microalbuminuria and hyperuricemia are significantly more prevalent among prehypertensive subjects as compared to normotensive subjects.
Background: This study was done to create awareness among people about the problems of Anemia and health care providers in further management. The aim of this study was to assess the prevalence, severity, risk factors of anemia among 2-12 years of aged children attending a hospital. Subjects and Methods: Blood and stool samples were collected from the patient. Among those children with hemoglobin <11 g/dl, were screened for iron deficiency anemia (serum ferritin estimation is done). Among these 500 children, 100 children with a hemoglobin level of 11gm/dl and serum ferritin <12 μg/l were taken up for detailed study. Results: A total of 138 males 62.7% were having hemoglobin less than 11.4 gm. /dl indicating anemia. total 230 female children about 66.5% were detected with anemia, 73 (31.73%) children had Hemoglobin levels less than 8 gm. /dl indicating severe anemia and about 49 (21.30%) children had moderate anemia and 31 (13.47%) had mild anemia and only 77 (33.47%) were having their hemoglobin concentration of greater than 11.5 gm. /dl were classified as non-anemic. Conclusion: Anemia was slightly more prevalent in girls of the same age group as compared to boys.
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