Aim and Objective: To study the serum prolactin levels and the serum TSH in primary infertile females. Material and Method:In this study, we investigated thirty women who were diagnosed cases of primary infertility, who attended the Biochemistry Department, Sir JJ Group of Hospitals, Mumbai, India, for hormonal evaluations. Thirty fertile women with similar ages were enrolled as the controls. The status of the thyroid dysfunction and the levels of serum prolactin were reviewed in infertile women and in the controls. The serum Prolactin and the thyroid stimulating hormone levels were measured by using Siemens kits in IMMULITE 1000 chemiluminescence immunoassays.Results: In our study, the serum prolactin levels in the infertile group were found to be high as compared to those in the control group and they were highly significant (p<0.0001). The serum TSH levels in the infertile group were found to be high, as compared to those of control group and they were highly significant (p<0.0001).

BACKGROUND It is a known fact that giving the blood helps the other in more than one way. One pint of blood given by the donor can save the lives of as many as three individuals. The aim of the study was to estimate the effect of lipid profile after 7 th , 30 th and 90 th days of blood donation. MATERIALS AND METHODS This is a descriptive study. 30 healthy volunteers were included in the study without any major illness. Total cholesterol was estimated by CHOD-POD method. HDLc was estimated by phosphotungstic acid method. TG was estimated by GPO-POD method. LDLc was estimated by using formula of Friedewald et al. RESULTS All the parameters of lipid profile, e.g. TC, LDL, VLDL except HDL was highly significantly decreased (p < 0.001) after 7 th and the effects continued till 30 th day after blood donation, which was highly significantly decreased (p < 0.05, HDL). It was significantly increased (p < 0.05) after 7 th and 30 th day of blood donation. At 90 th day, all values were normalised. CONCLUSION The act of blood donation has favourable hypolipidaemic effect even in normal healthy volunteers, which starts as early as 7 days and gets normalised by 90 days with continued raised levels of HDL.

Background: Smoking is associated increase in morbidity and mortality from various diseases. Increasing evidence suggests that chronic smoking adversely affects vascular and hormonal systems. Smoking plays a significant role in the development of atherosclerosis, thrombogenesis and vascular occlusion, which further adversely affects the prognosis of nephropathies. Aim and. Objectives: to estimate and compare the levels of hSCRP and microalbumin levels in smokers and non-smokers. Materials and Methods: Under aseptic precautions random venous blood sample of 2 mL was drawn from ante-cubital vein and collected in red top tube and serum was separated and analysed for high sensitivity C reactive protein (hSCRP). Early morning mid-stream urine was used for urine microalbumin estimation and the same sample was used for urine microscopy to exclude patients with urinary tract infection. Statistical Analysis: All statistical tests was performed using SPSS software. For comparisons of different variables student’s t-test and Chi-square test were be used. Pearson coefficient of correlation was used for assessment of relationship between variables. A p value <0.05 was considered statistically significant.