A large majority of cervical cancer (more than 95%) is due to the Human Papillomavirus (HPV). The HPV type 16 account more than half of cervical cancers Worldwide. This study investigated the sero-prevalence of HPV-16 IgG antibodies among women attending General Hospital Kagarko, Kagarko Local government, Kaduna State. Serum samples and questionnaires were administered to 110 women for collection of data. HPV-16 specific IgG antibodies were detected by the use of an HPV-16 virus-like particle ELISA. The highest HPV-16 IgG sero-positivity 24.5% (27/110), was found at the age >20-59 years and at 95% confidence interval. Sero-positivity increased from 9.5% in women having one lifetime sex partner to 62.5% in women with more than three sex partners (p=0.006). Age at first intercourse, number of lifetime sex partners, and having had sex with men who have multiple sex partners were significantly associated with HPV-16 IgG antibodies. These information on HPV sero-epidemiology will be important for designing prevention efforts including vaccine programs.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.