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Background Circular RNA (circRNA) plays key regulatory roles in the development of many diseases. However the biological functions and potential molecular mechanisms of circRNA in the injury and repair of intestinal mucosa in mice after severe burns are yet to be elucidated. Methods Cell counting kit-8 (CCK-8), 5-ethynyl-2′-deoxyuridine (EdU), wound healing and transwell assays were used to detect cell proliferation and migration ability. Real-time quantitative PCR was used to identify the expression of circRNA, microRNA and messenger RNA. Nuclear and cytoplasmic separation experiments were employed to perceive the location of circRNA_Maml2. Finally, in vitro and in vivo experiments were conducted to study the repairing effect of circRNA_Maml2 on the intestinal mucosa of mice after severe burns. Results When compared with the control group, the expression of circRNA_Maml2 was significantly reduced in the severe burn group. Furthermore, overexpression of circRNA_Maml2 promoted the proliferation and migration of CT26.wt cells in vivo and the repair of damaged intestinal mucosa in vitro. CircRNA_Maml2 acted as a sponge adsorption molecule for miR-93-3p to enhance the expression of frizzled class receptor 7 and activate the downstream Wnt/β-catenin pathway, thereby promoting the repair of the intestinal mucosa. Conclusions Our findings demonstrate that circRNA_Maml2 regulates the miR-93-3p/FZD7/Wnt/β-catenin pathway and promotes the repair of damaged intestinal mucosa. Hence, circRNA_Maml2 is a potential therapeutic target to promote intestinal mucosal repair.

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This preliminary study has shown that the application of a multimode sonographic technique (ie, 2D, 3D, and transrectal sonography) can provide unique evidence and imaging features of pelvic lipomatosis, which are comparable with CT for making a suggestive diagnosis of pelvic lipomatosis. Thus, multimode sonography may be the modality of choice for assessment of patients with a suspicion of lipomatosis.

Directional pattern is a clear visual representation form of antenna radiation characteristics. Taking a certain kind of shipborne radar as example, the basic principle of the directional pattern measurement was analyzed, the basic methods and execution scheme were introduced in detail. A directional pattern automatic testing system which was based on Lavbiew was researched on the basis of existed testing techniques, and finally the directional pattern automatic measurement was realized through the use of virtual instrument GPIB and serial interface techniques.

Subject to the delay restrictions of different traffic, a novel resource allocation based on traffic prediction is proposed for satellite communication. Firstly, different types of traffic are queued in the buffer with partition coefficient according to the priorities. Then, an access control algorithm is implemented by traffic prediction instead of demand. The theoretical analysis and simulation results show that new algorithm can efficiently improve delay performance of multi-type traffic in satellite resource allocation.

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Servo motor plays an important role in the system of measure and control radar. But the motor is easily spoiled because of mechanical wear and vibrating under at high load over a long period of time. And the examination is inconvenient. In order to make the motor circulate dependablely, we need monitor the motor on line, and analyze the fault. In this article we propose a method to collect the motor oscillation, through Matlab neural network training, the diagnose fault is displayed in LabVIEW interface. The experiment indicates that result of the method is accuracy and very effective.