In this study, antibody responses after equine influenza vaccination were investigated
among 1,098 horses in Korea using the hemagglutination inhibition (HI) assay. The equine
influenza viruses, A/equine/South Africa/4/03 (H3N8) and A/equine/Wildeshausen/1/08
(H3N8), were used as antigens in the HI assay. The mean seropositive rates were 91.7%
(geometric mean antibody levels (GMT), 56.8) and 93.6% (GMT, 105.2) for A/equine/South
Africa/4/03 and A/equine/Wildeshausen/1/08, respectively. Yearlings and two-year-olds in
training exhibited lower positive rates (68.1% (GMT, 14) and 61.7% (GMT, 11.9),
respectively, with different antigens) than average. Horses two years old or younger may
require more attention in vaccination against equine influenza according to the
vaccination regime, because they could be a target of the equine influenza virus.
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