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Introduction: A tenosynovitis is a rare form of tuberculosis. It may be overlooked or misdiagnosed due to non-specific findings. These delays in diagnosis and treatment can cause serious complications. Case Presentation: In these case reports, two patients with complaints of pain and swelling in the wrist flexor tendons received various diagnoses such as inflammatory arthritis and carpal tunnel syndrome. These patients who did not respond to the treatment were diagnosed with tuberculosis tenosynovitis as a result of the microbiological and histopathological evaluation. The patients showed significant improvement with antituberculosis treatment and surgical treatment was not needed. Conclusion: It is important for early diagnosis and prevention of appropriate complications in tuberculosis tenosynovitis.