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Hair fall provokes anxiety and distress, which reflects the symbolic and psychosocial importance of hair. Main reasons for hair loss are anagen phase, poor blood flow, sebum, emotional stresses, nerves disorders, aging, hair hygienic care pattern, infections, hormonal imbalance, pollution, radiation etc. Cereus grandiflorus (cactus) Flower extract very much pronounced with respect to hair fall control. It contains the higher amount of betacyanins and flavonolglycosides. Present study aimed to generate the authentic documents about the safety and efficacy of Cactus enriched hair oil performance on patients suffering from the hair fall disorders. Sixty alopecia patients were enrolled for the study with average age of 35.7 ± 10.8 years. Patients of either sex in the age group varied between 18 and 65 years. Overall clinical study results revealed that usage of herbal hair oil containing Cereus grandiflorus (cactus) Flower extract is effective and significantly reduce the hair fall. Efficacy was analyzed with changes in the intensity of hair fall over 12 weeks from baseline to treatment visits using Objective Improvement Evaluation Score and subjects response to Global Evaluation Score. None of the subjects had distressing hair fall at the time of enrolment. Cactus containing the higher amount of anti-oxidant potential and it helps the healthy sebum in the scalp and aromatherapy also plays a vital role in alopecia treatment. The gentle massage reduce the stress and increase the blood circulation, in addition to that many scientist proved that cactus oil helps to increase the blood circulation; higher blood circulation minimize the alopecia. Application /usage of herbal hair oil containing the Cereus grandiflorus (cactus) Flower extract is a safe and effective in terms of hair loss prevention. It helps for regenerate the new hair growth by continuous application of 12 weeks.

The human scalp is susceptible to microbial build-up if not thoroughly and frequently washed with the appropriate cleansing agents such as shampoos. Natural oils are presented in our scalp and it called as a sebum and it is a fuel/food for the dandruff-causing microbe. Malassezia feeds off these oils, breaking it down into by products, including oleic acid; formation of oleic acid is a starting/ kick point of dandruff. Approximately 50% people in the world sensitive to the oleic acid and affected by the dandruff. Overall clinical study results revealed that usage of tested anti-dandruff shampoo is effective and significantly reduce the dandruff fungi in scalp. Efficacy was analyzed with changes in the intensity of dandruff over 6 weeks from baseline to treatment visits using Visual Analogue Scale (VAS). The average response of Visual Analogue Scale for visit1 and visit 5 was 6.287 and 0.350 respectively. The average response/changes of Visual Analogue Scale score for Visit1 is 100.00 and Visit 2 having the score of 74.360; Visit 3 having the 47.924, Visit 4 having the score of 19.453 and Visit 5 was having the score of 5.567. It is concluded that there is statistically significant difference between the average response of Visual Analogue Score (VAS) between Visit 1 and Visit 5 which is indicative of remarkable improvement of dandruff over a period of 6 weeks. The tea tree oil in the formula act as a carrier to carry the actives in to the deeper part of the scalp; synergistic combination of natural and synthetic chemicals helps to control the dandruff. Overall study confirmed that the synergistic combination of synthetic anti-dandruff and natural ingredients plays a crucial role in control the anti-fungal, anti-inflammatory and local immune stimulatory actions.

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