Aim To evaluate the association between changes in platelet indices (platelet count, mean platelet volume, platelet distribution width) and development of preeclampsia. Materials and methods Two hundred pregnant women at 20 to 24 weeks of gestation with singleton pregnancy and normal blood pressure were enrolled after taking well-informed consent. At monthly intervals CBC (complete blood count) was done from 20 to 24 weeks till 40 weeks and 7 days after delivery. Data regarding changes in platelet indices with increasing gestation was collected and analyzed. Results Platelet count decreased significantly in patients with preeclampsia compared to normal pregnant patients (19.4% vs 7.4%). Mean platelet volume increased significantly in preeclampsia patients (44.5% vs 9.22%). Increase in PDW was observed significantly in patients with preeclampsia (47.19% vs 29.4%). Conclusion Patients with preeclampsia are more likely to have significant decrease in platelet count, increase in PDW and MPV. These changes can be observed at an earlier gestational age than significant rise in BP can be observed and are directly proportional to progressive rise in hypertension. Thus, estimation of platelet indices can be considered as an early, simple and cost-effective procedure in the assessment of severity of preeclampsia. How to cite this article Dadhich S, Agrawal S, Soni M, Choudhary R, Jain R, Sharma S, Saini SL. Predictive Value of Platelet Indices in Development of Preeclampsia. J South Asian Feder Obst Gynae 2012;4(1):17-21.

Objective: To analyze the cases of maternal mortality over a period of 3 years with regard to direct, indirect and associated causes and social correlates. Materials and methods:Retrospective evaluation of the cases with respect to causes, admission to mortality interval, age, parity, antenatal booking, socioeconomic status, etc. and systemic analysis of all contributing factors. Result and observation:A total of 66.67% of the deaths were due to direct causes with obstetric hemorrhage being the most common cause followed by puerperal sepsis. Anemia was the most important indirect cause followed by hepatitis and cardiovascular diseases. Conclusion:A large number of maternal deaths seem to be avoidable if we are able to strengthen our maternity and child health services. Equally important, however, remains the upgradation of the status of females in the society with emphasis on literacy and general health awareness.

Intracerebral hemorrhage (ICH) during antenatal period is an infrequent but serious complication. This is a case of elderly woman with pregnancy induced hypertension who developed spontaneous ICH during the thirty five week of pregnancy. She presented to our emergency department with altered sensorium, aphasia and hemiparesis. Intracerebral hemorrhage was diagnosed by MRI. Magnetic resonance angiography failed to identify an aneurysm or arteriovenous malformation. She underwent successful emergency cesarean section. In this case we report the rare Intracerebral hemorrhage (ICH) during antenatal period and its challenging complication, diagnosis and management.

Introduction: Postdated pregnancy is defined as pregnancy extended beyond 40 weeks of gestation or 280 days. FIGO and WHO defined post term pregnancy as a pregnancy which has gestational length of 294 days or more, Post term pregnancy is defined as pregnancy that has extended to or beyond 42 weeks of gestation, or estimated date of delivery (EDD)+14 days. Therefore we conducted this study to evaluate fetomaternal outcome in post dated pregnancies. Material & Methods: This was a retrospective hospital based study conducted on 400 pregnant women beyond 40 weeks of gestational age from the period of November 2018 to October 2019. A detailed history and clinical examination were recorded in performa from hospital records. Data pertaining to the onset of labour, mode of delivery, caesarean section due to fetal distress/ meconium stained liquor birth weight, Apgar score at 1minute and 5minute,NICU admission and perinatal death were analysed. The data obtained were entered in Microsoft excel and were analysed using appropriate statistical test (chi square test). P value of <0.05 was taken as significant. Results: Majority of cases belonged to rural area where total 57.3% cases were found while 171(42.7%) cases belonged to urban area. 184(46%) cases were booked and 216(54%) cases were unbooked. 260(65%) cases were referred from other centers, 140(35%) cases were not referred. 253(63.3%) cases were primigravida, 87(21.8%) cases were second gravida and 14.9% cases were multigravida.As a induction of labour oxytocin was used in 126(31.5%)cases, CP gel was used in 73(18.3%) of cases while miso was used in 26(6.5%) of cases. Conclusion: Maternal morbidity increased in the form of emergency LSCS, postpartum hemorrhage, instrumental deliveries, as the gestational age increased beyond 40 weeks. Maternal and fetal morbidity and mortality can be reduced by electively inducing pregnant women at 40 weeks as allowing them to continue beyond this gestational age has shown adverse feto-maternal outcomes. Keywords: Fetomaternal, LSCS, Maternal Morbidity

Objective: Active management of the third stage of labor (AMTSL) is a critical intervention for the prevention of postpartum hemorrhage (PPH), which is still the most common cause of maternal morbidity and mortality worldwide. The objective of the study is to compare the effect of intramuscular methylergometrine, rectal misoprostol, and low-dose intravenous oxytocin in the AMTSL in terms of amount of blood loss and duration of the third stage of labor, cost-effectiveness, and side effect profile. Materials and Methods: Seventy-five pregnant patients admitted in the maternity ward for vaginal delivery from February 2017 to February 2018 received either intramuscular methylergometrine (0.2 mg) or rectal misoprostol (400 mcg) or low-dose intravenous oxytocin (5 units oxytocin in 100 mL normal saline) for AMTSL. Data were recorded in three groups: Group A (methylergometrine), Group B (misoprostol), and Group C (oxytocin) consisting of 25 cases each. Results: Mean blood loss was found to be least in methylergometrine group (246.87 ± 65.44 mL) as compared to misoprostol (346.13 ± 58.35 mL) and oxytocin (334.5 ± 69.20 mL) ( P = 0.000) Mean duration of the third stage of labor was also least in methylergometrine group (6.21 ± 1.58 min) ( P = 0.0008). Conclusion: Although methylergometrine was found to have higher incidence of side effects such as nausea, vomiting, headache, and raised blood pressure, it was found to be the most effective drug for minimizing blood loss in the third stage of labor. In remote places where healthcare facilities are limited and drugs cannot be administered by parenteral route, rectal misoprostol remains an alternative.