Background: Vulval dermatoses may present with varied manifestations ranging from asymptomatic to chronic disabling conditions. The multifactorial nature of symptoms and physical expression of the disease on the vulva complicate the evaluation and management of genital dermatoses, thereby severely impairing the quality of life of patients. Objectives: To study the clinical patterns and socio-demographic features of vulval dermatoses and their impact on the quality of life using the dermatology life quality index (DLQI) questionnaire. Materials and Methods: Female patients of all age groups who attended our outpatient department (OPD) from October 2019 to March 2021 with vulval lesions were included in the study after a detailed history and complete examination. Based on sites of involvement, the lesions were classified as genital lesions alone, genital and skin lesions, oro-genital lesions, and oro-genital and skin lesions. DLQI score was assessed using the DLQI questionnaire. Results: In total, 520 patients were recruited for the study after following the inclusion and exclusion criteria. The most common age group was 31–40 years (33.65%). The majority of the patients were married (91.92%), housewives (82.88%), and illiterate (49.61%) women. The most common presenting symptom was itching (43%). The most common vulval dermatoses were infections, seen in 401 (77.11%) patients, followed by inflammatory diseases in 78 (15%) patients, and immunobullous diseases (1.53%). Patients with genital, skin, and oral involvement showed statistically significant higher DLQI scores ( P value < 0.05). Patients with immunobullous disorders had the highest mean DLQI scores. Limitations: As this study was a hospital-based study, the observations may not represent and reflect the general population. Conclusion: Patients with genital, skin, and oral lesions had the highest DLQI scores, indicating higher impact on the quality of life. Assessment of the disease’s impact on the quality of life is essential because it not only aids in early management but also helps in minimizing the duration of the ailment.
BACKGROUND Androgenetic alopecia has been associated with increased risk of coronary heart disease in various studies. Androgenetic alopecia is the most common type of alopecia in men., characterised by the transformation of thick terminal hair follicles in to thin vellus like hair follicles. It occurs under the influence of androgens in genetically predisposed individuals. The mode of inheritance is polygenic. The relationship between androgenetic alopecia and metabolic syndrome, is a known risk factor for atherosclerotic diseases. Metabolic syndrome is a cluster of inter related risk factors that increase the risk of atherosclerotic cardiovascular disease. Our study looked at the association between metabolic syndrome and androgenetic alopecia in the age group of 20-45 yrs. men. We wanted to study the association between androgenetic alopecia and metabolic syndrome. METHODS A descriptive cross-sectional study was done on men in the age group of 20 to 45 years. Two groups are taken in to the study. The first group is androgenetic alopecia group and the second group is non alopecia group. Study is undertaken for a period of 3 months, hence feasible sample size 30 is taken. Age of the study population is restricted to 20-45 years because incidence of androgenetic alopecia increases with age. Statistical association between androgenetic alopecia and metabolic syndrome was studied using students t test and chi square test SPSS version 20. RESULTS Metabolic syndrome was seen in 8 out of 30 samples (26%) in the androgenetic alopecia group, 4 out of 30 samples (13%) in nonalopecia group, p value is 0.015. Central obesity and HDL are elevated in most of the samples of androgenetic alopecia group. Limitation of our study was the small sample size. CONCLUSIONS High prevalence of metabolic syndrome is seen in men with androgenetic alopecia. Investigating for metabolic syndrome in patients with androgenetic alopecia is helpful for early detection and prevention of coronary artery disease.
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