Azadirachta indica (Neem) has a dynamic role in various problems associated with human health. Each part of the Neem tree has some medicinal property and is thus commercially utilizable. The plant parts such as leaves, flowers, seeds, fruits, roots and bark have been used traditionally for the treatment of inflammation, infections, fever, skin diseases and dental disorders. The aim of this study is to identify and characterize the vital bioactive compounds from the Neem sap by Gas chromatography and Mass spectroscopy (GC-MS). The GC-MS analysis of the Neem sap revealed the presence of 30 volatile compounds. Among the 30 compounds, the most predominant compounds are fatty acids like Hexadecanoic acid and Pentadecanoic acid. Hence, this current attempt forms a basis for the biological characterization and importance of the compounds which could be exploited for future development of drugs.
Super critical fluid extraction was employed for the extraction of inulin from chicory roots and Response Surface Methodology was used to optimize the effects of processing of extraction yield of inulin considering parameters such as solvent ratio, pressure (bar) and temperature (oC). Tri-dimensional response surfaces and optimal conditions were determined. Contour plots were determined from the mathematical model. In accordance with super critical fluid extraction, maximum inulin yield was obtained as 0.8% at the temperature of 40oC and 100 bar pressure. Conventional extraction technique yields a maximum inulin content of 6.22 % with a solvent ratio of 1:30 at a temperature of 70oC and time 30 mins while the yield of extract (Total soluble solids) was estimated to be 59.09%. Super critical fluid extraction may be used for the extraction of inulin from the roots of chicory for its use as a nutraceutical in functional applications.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.