In this prospective study, minimally invasive methods of proximal gastric vagotomy (PGV) were investigated in male Sprague-Dawley rats. Completeness of vagotomy by traditional operative therapy, by laser denervation of the gastric serosa, and by subserosal or transmucosal injections of chemoneurolytic agents was evaluated with postoperative Congo red testing, ulcerogenic stimulation of the gastric mucosa, and histochemical labeling of whatever vagal fibers remained in the gastric wall. Short-term results demonstrate that successful PGV can be performed with minimally invasive methods.
L i s t o f Figures L i s t o f Tables I n t r o d u c t i o n 1.1 Problem D e f i n i t i o n 1.2 Research Objectives 1.3 Experimental Approach 2. Theoretical Background and L i t e r a t u r e Review 2.1 Some D e f i n i t i o n s 2.2 Ambient Mixing 2.3 Passive Source Experiments 2.4 J e t I n j e c t i o n Experiments 3. D e s c r i p t i o n o f Experiments 3.1 The Hydraulic C i r c u i t 3.2 The Tracer I n j e c t i o n System 2 3.2.1 The Tracer 3.2.2 The I n j e c t i o n C i r c u i t 3.2.3 The I n j e c t o r s 3.3 Visual Observation o f t h e J e t 3.4 Method o f Measuring Concentrations 9 3.4.1 Sanipl i n g Technique 3.4.2 Concentration Detection C i r c u i t r y and Instruments 3.5 Typical Experimental Procedure 8 3.6 Descri p t i o n and Summary o f Experiments 9 4. Results and Discussion 4 7 4.1 S i n g l e J e t I n j e c t i o n s 47 4.1.1 C o e f f i c i e n t o f V a r i a t i o n 4 7 4.1.2 Optimum Momentum R a t i o 48 4.1.3 E f f e c t o f Alpha on the Mixing Distance 6 4.2 Dual J e t I n j e c t i o n s 4.2.1 C o e f f i c i e n t o f V a r i a t i o n 4.2.2 Optimum Momemtum R a t i o 61 4.2.3 Comparison w i t h Two P o i n t Sources 6 3 4.3 E f f e c t s o f J e t Misalignment 4.4 Tests w i t h Secondary Currents i n t h e Ambient Flow 4.5 Other Mu1 t i p l e -J e t I n j e c t i o n s 4.5.1 Uniform Flow 4.5.2 Flow w i t h Secondary Currents 5. A p p l i c a t i o n s 5.1 Pump Mixing 5 5.2 Pipe Mixing 5.
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