Least squares is used to fit a model to the individual match results in English football and to produce a home ground advantage effect for each team in addition to a team rating. We show that for a balanced competition this is equivalent to a simple calculator method using only data from the final ladder. The existence of a spurious home advantage is discussed. Home advantages for all teams in the English Football League from 1981-82 to 1990-91 are calculated, and some reasons for their differences investigated. A paired home advantage is defined and shown to be linearly related to the distance between club grounds.

The dismissive attitude of intellectuals toward conspiracy theorists is considered and given some justification. It is argued that intellectuals are entitled to an attitude of prima facie skepticism toward the theories propounded by conspiracy theorists, because conspiracy theorists have an irrational tendency to continue to believe in conspiracy theories, even when these take on the appearance of forming the core of degenerating research program. It is further argued that the pervasive effect of the “fundamental attribution error” can explain the behavior of such conspiracy theorists. A rival approach due to Brian Keeley, which involves the criticism of a subclass of conspiracy theories on epistemic grounds, is considered and found to be inadequate.

Bacterial virulence is a multifaceted trait where the interactions between pathogen and host factors affect the severity and outcome of the infection. Toxin secretion is central to the biology of many bacterial pathogens and is widely accepted as playing a crucial role in disease pathology. To understand the relationship between toxicity and bacterial virulence in greater depth, we studied two sequenced collections of the major human pathogen Staphylococcus aureus and found an unexpected inverse correlation between bacterial toxicity and disease severity. By applying a functional genomics approach, we identified several novel toxicity-affecting loci responsible for the wide range in toxic phenotypes observed within these collections. To understand the apparent higher propensity of low toxicity isolates to cause bacteraemia, we performed several functional assays, and our findings suggest that within-host fitness differences between high- and low-toxicity isolates in human serum is a contributing factor. As invasive infections, such as bacteraemia, limit the opportunities for onward transmission, highly toxic strains could gain an additional between-host fitness advantage, potentially contributing to the maintenance of toxicity at the population level. Our results clearly demonstrate how evolutionary trade-offs between toxicity, relative fitness, and transmissibility are critical for understanding the multifaceted nature of bacterial virulence.

The results of this study on home advantage in Australian rules football demonstrate that individual clubs have different home advantages. Traditional measures of home advantage as applied to whole competitions such as percentage of games won, and alternative measures such as average margin of victory for the home team, are calculated. Problems with these measures are discussed. Individual home advantages for each team are obtained using a linear model fitted to individual match margins; the resultant home advantages are analysed, and variations and possible causes or groupings of home advantage are proposed. It is shown that some models allowing different home advantages for different clubs are a significant improvement over previous models assuming a common home advantage. The results show a strong isolation effect, with non-Victorian teams having large home advantages, and lend support to the conclusion that crowd effects and ground familiarity are a major determinant of home advantage.

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