Abstract:Policy interest in the role of volunteering as a route to employment is enduring, with an assumption that links between volunteering, employability and employment are positive and straightforward. This has largely been supported by existing evidence, although there have been few longitudinal studies testing the theory. Analysing data from the British Household Panel Survey, we used multivariate techniques to explore the effects of volunteering on moves from being out of work into work; and on retention and wage progression for people in employment. We suggest that the relationship is complex: volunteering may have a positive effect on the labour market position of some individuals in some circumstances; for others it may have a negative, or no, effect. We offer some suggestions for the variations we found: the limitations of the dataset and our analysis; a limited concept of employability; and too narrow a view of volunteering and its impact.

Docetaxel chemotherapy in hormone-naïve mPC has significant toxicities, but has a similar effect on time to progression and overall survival as seen in randomised trials. Chemotherapy should be started at ≥3 weeks after ADT.

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INTRODUCTIONIn 2015 a special issue of this journal dedicated to illegal geographies contained six studies on the "relationships between clandestine economies and the political geographies of law enforcement" (Banister, Boyce and Slack, 2015, p. 365). The unifying thread between the papers was their focus on illegal drugs, with some interesting nods to the role of land use planning (Polson, 2015).More recently, in another journal De Leo (2017, p 216) discusses the "links between urban planning and organised crime". Responding to this emergent body of scholarship in geography and planning we unpack and problematize the links between illegal drugs and spatial planningthe drugs-planning nexus. Moreover, in developing a dialogue on drugs we set the context for a new research agenda for the territoriality, governance and planning of contemporary cityspaces. The first point to make is that a reading of the academic literature reveals the overwhelming majority of planners do not dedicate their mind or motives to the massive issue of illegal drugs.Historically planning discourse has been framed under umbrella narratives such as the public interest (Lennon, 2016) and sustainable development (Davidson and Gleeson, 2014); today the trendy concepts are competitiveness (Boland, 2014), climate change (Wilson and Piper, 2010), resilience (Mehmood, 2016), health and wellbeing (Tewdwr-Jones, 2017). The eclectic nature of modern spatial planning encompasses almost every issue facing the modern city, from children's diet to the futurity of the planet. We deliberately emphasise the adjective almost because there is one notable, to us perplexing, omission in the intellectual focus of planners. Souza (2006, p. 333, our inset) explains "drug trafficking [and use] is an important challenge…for urban planning".However, there is a limited number of papers addressing drugs from a planning perspective (e.g. ). Regarding practice, at different spatialities of the UK's planning framework health, wellbeing, crime and anti-social behaviour are mentioned; however, in comparative terms drugs, and their often deleterious spatial and social consequences, are not discussed in any substantive or systematic manner in any planning strategy or policy document. Thus, drugs seemingly do not occupy the mindset of planners in universities or councils. Even in an era of inter-professional working and healthy urban planning the issue remains disconnected from praxis. Instead, drugs are largely the focus of other social science disciplines (e.g. geography, sociology, criminology and economics) and responsibility of other public officials. 2For us drugs are a planning problem. This necessitates planning scholars and practitioners to be just as familiar with the drugs debate as they are with child obesity or global warming; i.e. moving beyond simplistic stereotyping of 'druggies' and sensationalist statements such as 'drugs cause crime' and 'drugs kill'. These at best misleading axioms, peddled by professionals (e.g. scientists, politicians and the police 1 ) an...

ImplicationsOestrogens in men are derived from the aromatisation of androgens therefore most androgen suppression strategies used to treat prostate cancer, such as LHRHa, cause a dual set of toxicities related to both androgen and oestrogen depletion. Using tE2 to produce castrate levels of testosterone in men with prostate cancer mitigates the side effects of LHRHa caused by oestrogen depletion (e.g. hot flushes, osteoporosis and adverse metabolic profiles), as well as avoiding the cardiovascular toxicity seen with oral oestrogen.Oestrogens administered transdermally should be considered for androgen suppression in the management of prostate cancer.

It is an axiom of good planning practice that procedure is informed by up-to-date research. Consequently, it is surprising to discover that there remains a dearth of specialised planning-enforcement literature relating to theory and implementation. In this paper an evaluation is given of the effectiveness of planning enforcement in Britain by reviewing existing legislative mechanisms and strategies employed by officials. Theoretical perspectives are drawn upon to suggest how the system might be improved through attention to the structural factors underpinning it.