Objective To evaluate transvaginal and transabdominal ultrasound scanning, with or without Doppler, as a diagnostic test for the accurate diagnosis of pelvic endometriosis.Methods The MEDLINE (1966-2001 and EMBASE (1980EMBASE ( -2001

PCOS cases and BMI/fat mass-matched control women are indistinguishable with respect to distribution of fat within visceral, abdominal sc, and gluteofemoral sc depots, despite significant differences in insulin resistance between these two groups.

• Patent cranial sutures appear hyperintense on "Black Bone" MRI • Prematurely fused cranial sutures are distinct from patent sutures • Minimal soft tissue contrast permits 3D-rendered imaging of the craniofacial skeleton.

The potential harmful effects of ionising radiation continue to be highlighted. Radiation reduction techniques have largely consisted of low-dose techniques rather than a shift to non-ionising methods of imaging. CT scanning is frequently employed for imaging the craniofacial skeleton despite being one of the key anatomical regions for radiation protection in view of the radiosensitive lens and thyroid gland. We describe a low flip angle gradient echo MRI sequence which provides high image contrast between bone and other tissues but reduces the contrast between individual soft tissues. This permits the "black bone" to be easily distinguished from the uniformity of the soft tissues. While maintaining a repetition time of 8.6 ms and an echo time of 4.2 ms, the flip angle which provided optimised suppression of both fat and water was identified to be 5°. The biometric accuracy of this sequence was confirmed using a phantom to obtain direct anatomical measurements and comparable CT scanning. The average discrepancy between black bone MRI measurements and direct anatomical measurements was 0.32 mm. Black bone MRI therefore has the potential to reduce radiation exposure by replacing CT scanning when imaging the facial skeleton, with particular scope for imaging benign conditions in the young.