Business incubators strive to develop robust business and social networks to bring value to their resident companies in the form of intellectual and material resources. Yet, information about what motivates resident companies to participate in networking activities and the obstacles they face in trying to build effective networks is limited. This study employs a communication perspective to examine the process of incubation in an award-winning university business incubator. Using a combination of network analysis and in-depth interviews, the case study reveals the nature of communication in the internal network of 18 resident companies and the incubator administrators. Despite being on the cutting edge of innovations in technology use, study findings reveal face-to-face interaction in the incubator is predominant. The physical proximity of resident companies at the incubator influences who they talk to the most, suggesting incubator site design is important in creating an entrepreneurial environment. The case study also indicates resident company motivations for networking include a strong desire for social support to help manage stress, security of membership in an in-group, and increased access to material or information resources. The primary obstacles residents face to participating in networking and building relationships with each other include extreme time limitations during the early start-up phase, lack of ongoing information about other residents, and lack of trust related to keeping information about innovations and funding sources secure. Implications of these findings and recommendations for incubator managers for building successful and sustainable communication networks conclude the article.
Nivolumab is an immune checkpoint inhibitor (ICI) currently in phase 3 clinical trials for hepatocellular carcinoma. The safety of ICIs in recipients of organ allotransplant is unclear, and several reports of fatal alloimmune injury after posttransplant ICI use have been published. We present the first published case of nivolumab used in the pretransplant setting for HCC resulting in fatal acute hepatic necrosis in the immediate postoperative period from a profound immune reaction likely propagated by nivolumab. Further investigation and significant caution are needed in the evaluation of patients awaiting transplant who are receiving ICI therapy.
Much of the theory guiding career development research is grounded in studies of men's careers in professional positions. In addition to largely ignoring the career experiences of women, the career literature pays little attention to overcoming barriers to career advancement in organizations-a challenge many women and men both face over the course of their career development. Using survey data, analyses of in-depth interviews, and a focus group discussion with female executives in the hightech industry, this study finds variations of three responses: exit, voice, and rationalizing to remain are used by women in response to career barriers. These responses form the foundation of a career barrier sensemaking and response framework presented in the study. Findings indicate that perceived organizational sanctioning of career barriers and the organization's commitment to the career advancement of other women also influence participants' responses to barriers and their strategies for sensemaking, respectively.
Background Head-and-neck cancers (hncs) often present at an advanced stage, leading to poor outcomes. Late presentation might be attributable to patient delays (reluctance to seek treatment, for instance) or provider delays (misdiagnosis, prolonged wait time for consultation, for example). The objective of the present study was to examine the length and cause of such delays in a Canadian universal health care setting. Methods Patients presenting for the first time to the hnc multidisciplinary team (mdt) with a biopsy-proven hnc were recruited to this study. Patients completed a survey querying initial symptom presentation, their previous medical appointments, and length of time between appointments. Clinical and demographic data were collected for all patients. Results The average time for patients to have their first appointment at the mdt clinic was 15.1 months, consisting of 3.9 months for patients to see a health care provider (hcp) for the first time since symptom onset and 10.7 months from first hcp appointment to the mdt clinic. Patients saw an average of 3 hcps before the mdt clinic visit (range: 1–7). No significant differences in time to presentation were found based on stage at presentation or anatomic site. Conclusions At our tertiary care cancer centre, a patient’s clinical pathway to being seen at the mdt clinic shows significant delays, particularly in the time from the first hcp visit to mdt referral. Possible methods to mitigate delay include education about hnc for patients and providers alike, and a more streamlined referral system.
Relationships with organizational stakeholders are especially problematic for nonprofits in times of planned change. Implementers of change initiatives must negotiate demands for their time and attention as well as attend to severe resource constraints. Interviews with nonprofit administrators are used as the basis for the development of six models of implementation communication adopted by nonprofit implementers in interacting with various stakeholder groups. The data are also used as a basis for theorizing about two communicative dimensions of the task situation—communication efficiency and consensus building—which may be used to predict implementers’ choices of approach to their communication with stakeholders.
Background Leukopenia is a frequent complication following kidney transplantation. Granulocyte colony‐stimulating factor (G‐CSF) has been used to accelerate white blood cell (WBC) count recovery; however, published experience in kidney transplantation is limited. Methods We retrospectively reviewed our kidney transplant recipients from January 2012 to September 2016 with a G‐CSF order to evaluate leukopenia management (defined as WBC <3000 cells/μL). Results Thirty‐six recipients were included. On average, G‐CSF treatment began at 98 ± 38 days. At G‐CSF initiation, mean WBC count was 1240 ± 420 cells/μL and absolute neutrophil count (ANC) was 653 ± 368 cells/μL. Mean G‐CSF dose was 4.6 ± 1.2 mcg/kg/dose (total 11.8 ± 9.0 mcg/kg), 77.8% of recipients were prescribed G‐CSF as outpatients, and overall, median time to WBC count recovery was 9 (IQR 4‐14) days. Changes in immunosuppression and prophylaxis regimens for leukopenia were also common. Within 1 month following leukopenia onset, no patients experienced acute rejection and 5 (14%) developed infection requiring hospitalization or opportunistic infection. Conclusion In kidney recipients with leukopenia, G‐CSF may be helpful to achieve WBC count recovery in addition to changes in immunosuppression and prophylaxis medications. Prospective, randomized data are still needed to determine optimal G‐CSF dosing in this population.
This paper is a response to scholars who have called for exploring and interrogating new strategies of data collection and new approaches to more traditional methods, such as interviewing in the context of the internet. Drawing on feminist standpoint theory, ‘reflexive email interviewing’ is proposed as a method for feminist research. The method is illustrated using a recent case study of email interviews with self-identified women who are members of World Pulse, an online community that aims to unite and amplify women's voices worldwide. Through this case study, issues of power and resistance in the researcher/researched relationship and of participant reflexivity are interrogated. Lastly, criteria for reflexive email interviewing are proposed, including 1) strategies to interrogate and disrupt power hierarchies within the research process, 2) researcher reflexivity as a continuous part of the research process, and 3) continued invitations for participants to directly reflect on and respond to the research process. Reflexive questions are offered for researchers to use during research design and in each phase of their research process to ensure reflexivity is achieved.
This article extends research on transnational feminist networks (TFNs), organizations that bring women together across national borders for collective action. A case study of World Pulse, a TFN with online community members from 190 countries that aims to amplify women's voices globally, reveals the nonprofit organization engages in ongoing reflexive practices to negotiate tensions related to voice. Using the analytical lens of postcolonial reflexivity, two themes of reflexive practices were identified: speaking from within (direct and formal inclusion of members' voices) and speaking for (staff displaying ethical consciousness around members' voices). Questions TFNs can ask to promote reflexivity are proposed.
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