Background and Purpose-Abrupt compliance changes and concomitant nonlaminar flow patterns may contribute to endothelial dysfunction and subsequent neointimal thickening. The aim of this study was to test the feasibility of wall mechanics measurement using B-mode ultrasound image analysis by dedicated software in the stented human carotid artery. Methods-Carotid Wallstents (Schneider) were placed in the extracranial carotid arteries of 15 patients. B-mode ultrasound examination was performed with a 7.5-MHz probe on the carotid artery upstream; at the proximal, mid, and distal stent levels; downstream from the stent; and on the contralateral internal and common carotid arteries. Carotid diameter (d) and systolic diameter changes (⌬d) were measured with a dedicated image processing system (IÔ version 3.1, IÔDP), while pulse blood pressure (⌬P) was measured. Diameter compliance (Cd) and distensibility coefficient (DC) were calculated as Cdϭ2⌬d/⌬P and DCϭ2⌬d/⌬P/d and compared between measurement sites. Results-The evaluation could be completed in 8 of 15 patients. Compliance was significantly lower at the proximal, mid, and distal stent levels (27.77Ϯ1.11, 27.38Ϯ1.08, 27.38Ϯ1.09ϫ10 Ϫ3 mm ⅐ kPa Ϫ1 ) than upstream (103.3Ϯ36.7ϫ10
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.