Progressive explosive-type RT was feasible in the included group of hip OA patients scheduled for THA and resulted in significant improvement in self-reported outcomes and increased leg muscle power.

Intervention by telephone support and counselling in the postoperative phase seems to benefit patients' improvement in health status.

Objective: To investigate 1-year postoperative effect of preoperative resistance training (RT) in patients undergoing total hip arthroplasty (THA) on patient-reported outcomes on activity and function and objective outcomes on muscle strength and physical performance. Design: A 3e12 months follow-up of a randomized controlled trial. Patients scheduled for THA were randomized into: RT-group, twice a week for 10 weeks prior to THA, or 'care-as-usual' (CG). Primary endpoint of this sequel analysis is HOOS-ADL at 12 months follow-up. Secondary outcome measures are; other HOOS subscales, knee-and hip muscle strength plus function (gait, ascending/descending stairs, and sit-to-stand) at three and/or 12 months. Clinicaltrials.gov: NCT01164111. Results: Eighty patients (70% women, 70.4 ± 7.6 years, BMI of 27.8 ± 4.6) were randomized to RT (n ¼ 40) or CG (n ¼ 40); data from 85% were available at 12 months. No superior effects were observed at 12 months for HOOS ADL (between-group change score [95%CI]) (2.6 [-4.2; 9.8], P ¼ 0.44) or remaining subscales. However, ascending (1.3 s [0.3; 2.3], P ¼ 0.01)) and descending stairs (1.6 s [0.3; 2.9], P ¼ 0.01) demonstrated additional effects. At 3 months clinically relevant change-scores in favour of RT was observed on HOOS-Sport/Rec (10.5 points [1.4; 19.6], P ¼ 0.023), together with higher knee strength of the affected side (14.6 Nm [6.3; 22.9], P < 0.001), and selected outcomes of physical function. Conclusions: At 12 months after surgery, there was no additional effect of preoperative RT compared with THA alone, but rehabilitation was accelerated at 3 months.

In 497 children with 528 hernia and 190 boys with 241 maldescended tests, outpatient operation was performed in 96.5% and 92.6% of the patients with an immediate surgical complication rate of 1.5% and 0% respectively. No wound infection was observed and the long term result was satisfactory with 3.7% hernia recurrences and 90% of the tests localized in the bottom of scrotum. Orchiopexy at about two years of age and early herniotomy, irrespective of age, is recommended and surgery may safely be carried out on an outpatient basis.

Incorporation of a frozen human bone allograft requires osteoclast activity and ingrowth of recipient osteoblast precursors. We examined the effects of allografts on human osteoblasts. Allografts stimulated a release of factors from normal human osteoblast-like cells, capable of inducing osteoclastic bone resorption in vivo. Further allografts inhibited osteoblast proliferation in cultures. The response was detectable within 4 days of culture and was still present after 3 weeks. Devitalized bone autografts had a similar effect. This suggests that bone bank grafts may induce a resorptive reaction at the recipient site by stimulating release of factors from osteoblasts capable of inducing osteoclastic resorption. The storage temperature was crucial for preservation of the response, since the activity was lower in allografts stored for 6 months at -20 degrees C than in those stored at -80 degrees C.