Introduction: Periodontal diseases are advocated to show adverse pregnancy outcomes. Hence in our study we aim to conduct a systematic review of the previous systemic reviews studying the association between periodontal disease and adverse pregnancy outcomes. Material and methods: We searched online databases up to November 2016 for the previous Systematic reviews of studies comparing pregnancy outcomes among women with and without periodontal disease were eligible for inclusion. Primary outcomes were maternal mortality, preterm birth, and perinatal mortality. Results: From the 23 none reported the association between periodontal disease and maternal or perinatal mortality. Systematic reviews with the lowest risk of bias consistently demonstrated positive associations between periodontal disease and preterm birth, low birth weight, preeclampsia, and preterm LBW. Based on these figures, estimated population- attributable fractions for periodontal disease were 5% to 38% for preterm birth, 6% to 41% for LBW, and 10%to 55% for preeclampsia. Due to substantial overlap in included primary studies, we could not combine results across reviews. Conclusion: We can conclude that pregnant women with periodontal disease are at increased risk of developing preeclampsia and delivering a preterm and/or LBW baby.
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