Dento-maxillary disharmony is characterized as disproportion between tooth size and dental arch. This case report describes the treatment progress of a patient with dento-maxillary disharmony with Class I malocclusion using fixed orthodontic appliances. The patient is a 19-year-old female who came with chief complaint of crowding and ectopic upper canines. Correction of crowding and deep bite was achieved by fixed appliance with extraction. In Class I malocclusion, severity, etiology, and type of disharmony guide the treatment plan for optimal results
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