Abstract-Identification of a low-level point radiation source amidst background radiation is achieved by a network of radiation sensors using a two-step approach. Based on measurements from three sensors, the geometric difference triangulation method is used to estimate the location and strength of the source. Then a sequential probability ratio test based on current measurements and estimated parameters is employed to finally decide: (i) presence of a source with the estimated parameters, or (ii) absence of the source, or (iii) insufficiency of measurements to make a decision. This method achieves the specified levels of false alarm and missed detection probabilities, while ensuring close to minimal number of measurements to reach a decision. This method minimizes the ghost-source problem of the current estimation methods and achieves lower false alarm rate compared to current detection methods. This method is tested and demonstrated using: (a) simulations, and (b) a test-bed that utilizes the scaling properties of point radiation sources to emulate high intensity ones that cannot be easily and safely handled in experimentation.
Motivation: With rapidly expanding protein structure databases, efficiently retrieving structures similar to a given protein is an important problem. It involves two major issues: (i) effective protein structure representation that captures inherent relationship between fragments and facilitates efficient comparison between the structures and (ii) effective framework to address different retrieval requirements. Recently, researchers proposed vector space model of proteins using bag of fragments representation (FragBag), which corresponds to the basic information retrieval model.Results: In this article, we propose an improved representation of protein structures using latent dirichlet allocation topic model. Another important requirement is to retrieve proteins, whether they are either close or remote homologs. In order to meet diverse objectives, we propose multi-viewpoint based framework that combines multiple representations and retrieval techniques. We compare the proposed representation and retrieval framework on the benchmark dataset developed by Kolodny and co-workers. The results indicate that the proposed techniques outperform state-of-the-art methods.Availability: http://www.cse.iitm.ac.in/~ashishvt/research/protein-lda/.Contact: ashishvt@cse.iitm.ac.in
Identification of a low-level point radioactive source amidst background radiation is achieved by a network of radiation sensors using a two-step approach. Based on measurements from three or more sensors, a geometric difference triangulation method or an N-sensor localization method is used to estimate the location and strength of the source. Then a sequential probability ratio test based on current measurements and estimated parameters is employed to finally decide: (1) the presence of a source with the estimated parameters, or (2) the absence of the source, or (3) the Author's address: J.-C. Chin: email: jcchin@cs.purdue.edu. c 2010 Association for Computing Machinery. ACM acknowledges that this contribution was authored or co-authored by a contractor or affiliate of the U.S. Government. As such, the Government retains a nonexclusive, royalty-free right to publish or reproduce this article, or to allow others to do so, for Government purposes only. Permission to make digital or hard copies of part or all of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies show this notice on the first page or initial screen of a display along with the full citation. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, to republish, to post on servers, to redistribute to lists, or to use any component of this work in other works requires prior specific permission and/or a fee. Permissions may be requested from Publications Dept., ACM, Inc., 2 Penn Plaza, Suite 701, New York, NY 10121-0701 USA, fax +1 ( insufficiency of measurements to make a decision. This method achieves specified levels of false alarm and missed detection probabilities, while ensuring a close-to-minimal number of measurements for reaching a decision. This method minimizes the ghost-source problem of current estimation methods, and achieves a lower false alarm rate compared with current detection methods. This method is tested and demonstrated using: (1) simulations, and (2) a test-bed that utilizes the scaling properties of point radioactive sources to emulate high intensity ones that cannot be easily and safely handled in laboratory experiments.
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