A vaginal obstruction often occurs as a result of complication in women who had previously undergone an excision of a transverse vaginal septum. Her we are reporting a case of 12 years old unmarried girl presented with complaint of secondary amenorrhea and cyclic pain lower abdomen since two months. She was operated for cryptomenorrhea four months back. On examination under anaesthesia Thick scarred septum was present in vaginal canal about 6-7 cm from vaginal introitus .After sharp dissection hematocopos bulge seen and drained, residual scar tissue excised , posterior and anterior vaginal wall reconstructed. Vaginal mould inserted to maintain patency.
The aim of this study is to Evaluation of Efficacy and Safety of Bepotastine Besilate 0.15% Ophthalmic Solution in Patients of Vernal
Keratoconjunctivitis (VKC). This was a prospective, open label and randomized clinical study. Fifty patients of vernal
keratoconjunctivitis between 6 to 20 years of age of either sex willing to give informed consent were enrolled in the study. Patients
received Bepotastine besilate (0.15%) eye drops twice daily for 8 weeks. Symptoms scoring and signs scoring of VKC were recorded
on baseline and at the time of follow up at 4 and 8 weeks. Safety assessments were also done in the drug group during the study
period for any serious adverse effects. After the 2 months of drug therapy, patients showed improvement in the symptoms and signs
scoring of Vernal keratoconjunctivitis. There was statistically significant difference between the treatment group at 4th and 8th week.
The drugs were well tolerated without any serious adverse effect. Bepotastine besilate ophthalmic solution were found to be effective
in alleviating the clinical symptoms and signs of VKC.
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