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BACKGROUND Arterial hypertension and blood pressure level are associated with cognitive impairment. Susceptible people, especially cerebral ischaemia are having more severe cognitive impairment. Elevated blood pressure for long term contributes to cognitive impairment in later life. The aim of this study is to determine the cognitive dysfunctions in essential hypertensives. MATERIALS AND METHODS It was a descriptive cross-sectional study that was conducted among 300 subjects who were diagnosed as essential hypertensives were chosen by simple random sampling from the inpatient and outpatient facility of Department of Medicine, Father Muller's Medical College. The socio-demographic data of hypertensives was collected on a semi-structured proforma. Patients were assessed for cognitive dysfunctions using the Standardised Mini Mental Status Examination (SMMSE) and Brief Cognitive Rating Scale (BCRS). Data was analysed using SPSS 18 software. RESULTS Mean age group of patients was 51.67 years, majority of the patients were males and were urban domicile. Majority of patients had primary level of education. Majority of patients had positive relation between cognitive deficiency and their hypertensive status was measured using Standardised Mini Mental Status Examination (SMMSE) and Brief Cognitive Rating Scale (BCRS). CONCLUSION The study showed that there are significant cognitive deficits in hypertensives. SMMSE (Standardised Mini Mental Status Examination) and BCRS (Brief Cognitive Rating) Scales were used to measure Cognitive deficits, which were very closely related to hypertension.

BACKGROUNDAlcohol de-addiction is a cornerstone in the treatment of alcohol dependence syndrome. Following de-addiction therapy many patients relapse and only few patients maintain abstinence. The clinical, demographic variables have been reported to play an important role in the dynamics of relapse and abstinence after de-addiction in many studies, but there is no clear cut association between the variables and outcome till date, so the present study was planned. MATERIALS AND METHODSInitially, all study subjects in the study were subjected to alcohol detoxification and later to alcohol de-addiction therapy. After de-addiction patients were recalled for evaluation for period of three months. The sociodemographic data and details of clinical variables related to alcohol use were obtained in a pre-structured pro forma prepared in the Department for the purpose of the study. Severity of Alcohol Dependence Questionnaire (SADQ-C) was used in the study to assess the severity of alcohol dependence in the study subjects. RESULTSThere was no statistical significance result observed in relation to any demographic variables, clinical variables and outcome (relapse/abstinence to alcohol). CONCLUSIONIn this study, no significant association was found between sociodemographic variables, clinical variables and the outcome.

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