Highlights
Young adult COVID-19 patient presented with acute abdomen.
Evaluation of patient revealed splenomegaly, splenic rupture and hemoperitoneum.
Patient recover with conservative management.
Colorectal cancers in young are in increasing trend. Young patients tend to ignore symptoms and present at advanced stage due to aggressive tumour biology, and also due to traditional dictum of routine screening after >50 years these groups of patients are given less priority. The objective of our study was to estimate the burden of problem among young population and increase awareness among medical personnel and general population of early detection for disease. We conducted retrospective cross sectional study using whole sampling method among patients operated by single gastrointestinal surgery unit. Demographic details, malignancy information, surgical procedure and histopathological examination were studied. All cases admitted as colorectal cancer from 2013 to 2017 at gastrointestinal surgery unit of Shree Birendra Hospital were included. The collected data were entered in SPSS version 16 and analyzed. Likelihood of occurrence of adenocarcinoma was studied using logistic regression model. Among total 104 cases operated, only 99 cases were having complete data with median age: 55 years. Thirty seven percent of the individuals having colorectal malignancies were younger than 50 years. Rectum was the commonest site (52, 52.5%) for occurrence of colorectal malignancy. Males were 1.493 (0.402-5.545) times more likely to have colorectal adenocarcinoma than females. Young age (<50 years) was associated with an increased likelihood of colorectal adenocarcinoma {OR=1.771(0.443-7.233)} than older people. Colorectal cancer in young age is in increasing trends. Increasing awareness among medical personnel and general population is must for early detection.
Introduction: Gynecomastia is a benign condition of the male breast with glandular tissue proliferation. It can be physiologic or pathologic and many a times manifestation off underlying chronic pathology. Its treatment is selected based on cause, age and grade with surgical or pharmacological modalities. Periareolar incision with liposuction is the choice for higher grade gynecomastia.Methods: Patients record of Gynecomastia undergoing surgery for last two years from a tertiary hospital was reviewed retrospectively. Detail clinical evaluation and appropriate investigations obtained from medical records. Patients with chronic liver and renal disease, hyperthyroidism, alcoholics and patients on medical treatment as anabolic steroids were excluded from the study. Treatment of gynecomastia and its outcome was recorded and entered in excel and analyzed.Results: Among 33 patients enrolled, nineteen had unilateral gynecomastia whereas 14 patients had bilateral gynecomastia. Of them 10 were of Simons grade I, 17; IIA and 6; of IIB. Among operated patients mean age was 53.24 years.Conclusions: Periareolar incision with liposuction is the treatment of patient choice for higher gynecomastia due to its better outcome in terms of complication and patient satisfaction.
Introduction: Hepatocellular Carcinoma (HCC) is a common malignancy of gastrointestinal tract presenting in clinical practice. The common etiologies are hepatitis B virus (HBV), hepatitis C virus (HCV) and alcohol consumption. Treatment of HCC is multimodality based on Barcelona Clinic Liver Cancer (BCLC) staging system. The aim of the article is to study the demographic, clinico-radiological profile and treatment patterns of HCC patients.
Methods: This is a retrospective cross sectional study of patients diagnosed as HCC at Shree Birendra Hospital, Chhauni, Kathmandu, Nepal from April 2017 to March 2020. The study was approved by Institutional Review Committee. Data were collected for demography, clinical feature, histology, HBsAg status, serum AFP values, radiological findings and treatment details from hospital record. Data were analysed using Excel 2010 and SPSS v 21.
Results: Total of 36 patients diagnosed with HCC were included for analysis. There was a male predominance (72.22%) and the mean age was 66.75 ± 12.02 years. Pain abdomen and jaundice were present in 63.89% and 38.89% respectively at presentation and features of chronic liver disease (CLD) were evident in 83.33%. HBsAg was present in 44.44% of HCC. Location of tumour was primarily in right lobe (80.56%) and size of lesion varied greatly. Tissue diagnosis was obtained in 52.78% patients. Chemotherapy option was limited to Sorafenib.
Conclusions: HCC is more prevalent in older males. The common modes of presentation were pain abdomen and jaundice. Most of the HCC had underlying CLD and were advanced. Sorafenib was the mainstay of treatment in advanced HCC.
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