Nanoparticles research is at the forefront because of its enormous technological potentialities. Through
the hydrothermal method, yttrium oxide nanoparticles having multiform morphologies are successfully
synthesized. The morphology, structure, photoluminescence properties, and functional groups of these
nanoparticles were studied through scanning electron microscopy (SEM), powder X-ray diffraction
(PXRD), Fourier-transform infrared spectrometry (FTIR), photoluminescence spectroscopy (PL) and
UV-Visible (UV-Vis) analyses. The XRD results showed that the neat samples have cubic Y2O3 structure.
SEM micrographs revealed that the samples comprised aggregated nanoparticles having different
sizes and shapes. The UV-Vis spectra indicated that the absorption peak position shifted towards the
lower wavelength with a decrease in the particle size because of the changing surface structures and
morphologies. Photoluminescence spectra showed a PL emission with a broad peak at approximately
564 nm, when the sample was excited by 280 nm wavelength. FTIR and EDAX spectra confirmed the
presence of metal oxides. Yttrium oxide nanoparticles can counteract the influence of oxidative
metabolites and present an antioxidant activity with the IC50 of 86.84 μg/mL. These properties indicated
that these nanoparticles have a potential in biomedical and optoelectronic applications.
Herein, we demonstrate synthesis of Yttrium Oxide (yttria) nanoparticles of 0.1, 0.2, 0.3 and 0.4 M concentrations by hydrothermal method and characterized using various techniques. Powder XRD analysis showed that the as-prepared nanoparticles have cubic Y2O3 structure with an average crystallite diameter of 34-58 nm. SEM micrographs depicted that agglomerated yttria nanoparticles of different morphological properties and particles in size. The occurrence of metal Oxide is affirmed using FTIR and EDX analysis. The Yttrium Oxide nanoparticles showed better antimicrobial activity against ADCP declared harmful bacteria pathogens such as E. Coli, S. paratyphi, S. aureus, and S. pyogenes. Further, the yttrium oxide nanoparticles revealed better anticarcinogenic activity against MCF-7 cell line with IC50 value 47.07 μg/ml. From these findings, the nanoparticles of Y2O3 are candidates to be used as potential alternatives in antitumor therapy.
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