Background: In a PICU set up the reported incidence of MODS is 11-56% and the Odds of death in children with MODS 11.3. In a resource limited setting, mortality prediction becomes important within the first 3 days of PICU stay for financial burden plays a big role in these decisions. The PELOD score has been validated as an outcome measure when recorded daily. In this study, validation of the PELOD score on just 2 days i.e. at baseline (day 0) and after 48hrs (day 2) and the difference between the two was studied to predict short term mortality as an outcome by the end of 7 days. Aim: Prediction of mortality on seventh day with PELOD scoring on Day-0 and Day-2 in children with Multi Organ Dysfunction Syndrome in a tertiary care PICU. Materials & Methods: A prospective longitudinal observational cohort study was carried out in a 20 bedded Indian PICU. Inclusion criteria included children age 1 month to 12 years, the presence of MODS and a PICU stay > 24 hrs. Once an inclusion criterion is met data was collected from the patients in PICU & entered in EXCEL 2013 for calculation of PELOD & PRSIM.
Human brucellosis is a zoonotic infection, mostly caused by B. melitensis and usually presents as an acute febrile illness. Once considered rare in children, it is now recognized that brucellosis can affect persons of all ages, especially in areas where B. melitensis is the predominant species. Complications may affect any organ system. On the other hand Secondary Hemophagocytic lymphohistiocytosis (SHLH) can occur due to systemic infections, immunodeficiency, and underlying malignancies. (SHLH) is histologically characterized by excessive proliferation and activation of histiocytes or macrophages. Brucellosis associated with SHLH should be suspected whenever there is a prolonged fever along with hepatosplenomegaly and pancytopenia.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.