Ðepartment of Radlology , National Medical CenterThe incidece of primary lung cancer is increasing in our country This presentation is an attemot to co rrelate a useful diagnosis with radiological findings of primary lu ng cancer.Histologically proved 210 cases of prima 까 lung cancer during the period of 15 years were reviewed with plain chest films, tomogram , bronchgram and pulmonary angiogram .The results are as follow :1. Mal e to Female sex ratio was 4: 1. Incidence was most cominon in 5th decade as 40%. 4. In mass size: Average diameter of mass was m9st was 5.3cm .Hilar mass was see n in 48 cases. Hilar mass was most frequent finding in small cell Ca. and the peripheral mass in adeno Ca.5. Cavitary lung Ca. was 26 cases (12.4 %) and most cases had relative thick wall and its mean thickness was 3.6mm.6. Coexistence of pulmonary tuberculosis and lung cancer was 22 cases (10.5 %), and most common in epidermoid cell Ca. as 16 cases.7. Other findings include metastsis to Iymphnode, bone and other organ, and pleural effusion.
Background:As stated in 'The Action Strategy for Tuberculosis-Free Korea,' last March, high-throughput, large-scale analytical instruments for interferon gamma release assays (IGRA) are demanded by many clinical laboratories using the QuantiFERON-TB Gold In-Tube assay (Cellestis/Qiagen, Australia). Agility (Dynex Technologies, USA) is an automated high-throughput enzyme linked immunosorbent assay analyser. The present study aimed to evaluate its accuracy and speed. Methods: Pooled plasma was prepared using samples obtained after IGRA testing. Analyses of precision, linearity, cut-off evaluation, and comparison with conventional methods were performed for multiple Agility instruments according to the Clinical and Laboratory Standards Institute EP5-A3, EP6-A, EP9-A3 and EP12-A2 guidelines. The turnaround time and throughput were also analysed. Results: The coefficient of variation range was 2.48%-4.0%, 7.01%-11.17%, and 9.69%-14.84% for the repeatability, between-run precision, and between-day precision analyses, respectively. The linearity ranged from 0 to 10.541. Comparison analysis presented a high concordance of Agility with the conventional instrument, DS2 (Dynex Technologies), and manual method for IGRA. The cut-off value of 0.35 IU/mL was well compatible with the C 50 . It was identified that the C 50 ±20% contained the C 5 -C 95 interval. The average turnaround time was 3.84 hours, from the submission of pre-treated samples to the reporting of results. The throughput was determined to be 290 tests during a routine working time of 8 hours. Conclusions: Agility showed high precision, linearity, concordance, and had a 2.5 times faster throughput than with the conventional and manual method. It could be useful for large-scale IGRA testing in latent tuberculosis infection screening project. Samples within C 50 ±20% are suspected to show relatively low reporducible results of high inversion between postivie and negative.
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