Herein, we demonstrate an efficient protocol for transfer hydrogenation of ketones using methanol as practical and useful liquid organic hydrogen carrier (LOHC) under Ir(III) catalysis. Various ketones, including electron‐rich/electron‐poor aromatic ketones, heteroaromatic and aliphatic ketones, have been efficiently reduced into their corresponding alcohols. Chemoselective reduction of ketones was established in the presence of various other reducible functional groups under mild conditions.
Allenyl carbonate was used as a 1,3-butadiene surrogate
to develop
a photocatalytically sustainable protocol for cobalt-catalyzed crotylation
of aldehydes. The developed method tolerated a wide range of aromatic
and aliphatic aldehydes with retention of functional groups under
mild conditions and produced good-to-excellent yields of crotylated
secondary alcohols. Based on preliminary mechanistic studies and literature
precedents, a plausible mechanism is proposed.
The merger of transition metal catalysis and photocatalysis has emerged as a versatile platform which opened the gateway to diverse low energy pathways for several synthetic transformations. On the other...
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